Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 8/20 | 0.58 |
| ▸ | NPC1 | O15118 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.54 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12436031 | 0.87 | MAPK1 (0.57) | RAB9ANPC1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL17507526 | 0.86 | KMT2A (0.63) | RXFP1RAB9ANPC1ALDH1A1TP53 | |
| SCHEMBL12435954 | 0.85 | KMT2A (0.55) | RAB9ANPC1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL12435965 | 0.85 | KMT2A (0.56) | RAB9ANPC1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL12435909 | 0.81 | ATM (0.52) | ALDH1A1TP53SMN1; SMN2KMT2APKM | |
| SCHEMBL12435962 | 0.81 | MAPT (0.49) | RAB9ANPC1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL12435980 | 0.81 | NAMPT (0.50) | RAB9ANPC1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL12435991 | 0.79 | MAPT (0.47) | RAB9ANPC1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL12435952 | 0.79 | POLB (0.43) | RAB9ANPC1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL12435956 | 0.79 | SMN1; SMN2 (0.42) | RAB9ANPC1ALDH1A1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178108-A1 | Group of amino substituted benzoyl derivatives and their preparation and their use | Institute of Medicinal Biotechnology Academy of Medical Science (CN) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178108-A1 | Group of amino substituted benzoyl derivatives and their preparation and their use | CUL3, APOBEC3G, BRPF3 | RXFP1 4732/4885RAB9A 1374/4885NPC1 3314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.