Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12435954 | 0.88 | KMT2A (0.55) | KMT2AMEN1CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL12436030 | 0.87 | MEN1 (0.58) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12436031 | 0.85 | MAPK1 (0.57) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12435951 | 0.85 | RXFP1 (0.60) | KMT2AMEN1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL12436028 | 0.83 | MAPT (0.58) | KMT2AMEN1CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL12435970 | 0.81 | TRPV1 (0.54) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL12435955 | 0.81 | SMN1; SMN2 (0.42) | KMT2AMEN1CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL12435909 | 0.81 | ATM (0.52) | KMT2AMEN1CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL12435962 | 0.81 | MAPT (0.49) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12428714 | 0.80 | MAPT (0.45) | KMT2AMEN1CYP1A2CYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178108-A1 | Group of amino substituted benzoyl derivatives and their preparation and their use | Institute of Medicinal Biotechnology Academy of Medical Science (CN) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178108-A1 | Group of amino substituted benzoyl derivatives and their preparation and their use | CUL3, APOBEC3G, BRPF3 | KMT2A 964/4885MEN1 4747/4885CYP1A2 2309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.