Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.43 |
| ▸ | CHKA | P35790 | 1/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.39 |
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 5/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13761383 | 0.97 | GRM2 (0.45) | GRM2CHKAPTGES2PTGESTBXAS1 | |
| SCHEMBL8508687 | 0.92 | RARB (0.44) | GRM2CHKAPTGES2PTGESTBXAS1 | |
| SCHEMBL26036249 | 0.90 | CHKA (0.43) | GRM2CHKARARBHTR2AAPP | |
| SCHEMBL16257975 | 0.88 | PDE3B (0.42) | CHKARARB | |
| SCHEMBL3158940 | 0.88 | CYP1A2 (0.42) | GRM2CHKAPTGES2PTGESTBXAS1 | |
| SCHEMBL17586079 | 0.87 | RARB (0.43) | GRM2CHKAPTGES2PTGESTBXAS1 | |
| SCHEMBL9270795 | 0.86 | APP (0.41) | GRM2CHKAMCHR1PSEN1PSEN2 | |
| SCHEMBL10981111 | 0.86 | CHKA (0.45) | GRM2CHKARARBHTR2A | |
| SCHEMBL3259316 | 0.85 | ESR1 (0.40) | GRM2CHKAPTGES2PTGESTBXAS1 | |
| SCHEMBL20886693 | 0.85 | LMNA (0.43) | CHKARARBPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160075949-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT CONTAINING THE SAME | DIC CORPORATION (JP) | 2016-03-17 | — | — | US | disclosed |
| EP-2085454-B1 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2011-08-10 | — | — | EP | disclosed |