Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.32 |
| ▸ | RET | P07949 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.31 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12436928 | 0.86 | PREP (0.41) | PREPJAK1CHRM2CHRM1CHRM3 | |
| SCHEMBL12436556 | 0.86 | PREP (0.41) | PREPJAK1CHRM2CHRM1CHRM3 | |
| SCHEMBL16062569 | 0.85 | PREP (0.40) | PREPJAK1CHRM2CHRM1CHRM3 | |
| SCHEMBL12436385 | 0.84 | PREP (0.42) | PREPJAK1CHRM2CHRM1CHRM3 | |
| SCHEMBL17066303 | 0.84 | PREP (0.42) | PREPJAK1CHRM2CHRM1CHRM3 | |
| SCHEMBL12436927 | 0.84 | PREP (0.41) | PREPJAK1CHRM2CHRM1CHRM3 | |
| SCHEMBL12436783 | 0.81 | CYP3A4 (0.38) | — | |
| SCHEMBL16062559 | 0.81 | KCNK3 (0.41) | PREPJAK1CHRM2CHRM1CHRM3 | |
| SCHEMBL18426928 | 0.81 | KCNK3 (0.41) | PREPJAK1CHRM2CHRM1CHRM3 | |
| SCHEMBL889338 | 0.81 | KCNK3 (0.41) | PREPJAK1CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091532-A1 | HEPATITIS C INHIBITOR COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-04 | — | — | WO | disclosed |