Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | CCR3 | P51677 | 2/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.51 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12437387 | 0.95 | MEN1 (0.61) | MEN1KMT2ASLC5A7KDM4EALDH1A1 | |
| SCHEMBL12437516 | 0.90 | HRH3 (0.60) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12437392 | 0.90 | KDM4E (0.55) | MEN1KMT2ASLC5A7KDM4EALDH1A1 | |
| SCHEMBL12437365 | 0.90 | MEN1 (0.61) | MEN1KMT2ASLC5A7ALDH1A1CCR3 | |
| SCHEMBL12437534 | 0.89 | KMT2A (0.63) | MEN1KMT2ASLC5A7ALDH1A1CCR3 | |
| SCHEMBL12437356 | 0.87 | MEN1 (0.64) | MEN1KMT2ASLC5A7CYP2C9CYP2C19 | |
| SCHEMBL12437527 | 0.86 | MEN1 (0.63) | MEN1KMT2ASLC5A7CYP2C9CYP2C19 | |
| SCHEMBL12437362 | 0.86 | MEN1 (0.63) | MEN1KMT2ASLC5A7CYP2C9CYP2C19 | |
| SCHEMBL12437431 | 0.85 | MEN1 (0.58) | MEN1KMT2ASLC5A7KDM4EALDH1A1 | |
| SCHEMBL12437552 | 0.85 | MEN1 (0.65) | MEN1KMT2ASLC5A7ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178066-A1 | Hydroxypiperidine derivatives and uses thereof | AVALON PHARMACEUTICALS | 2011-07-21 | — | — | US | disclosed |
| US-20110178066-A1 | Hydroxypiperidine derivatives and uses thereof | AVALON PHARMACEUTICALS | 2011-07-21 | — | — | US | disclosed |
| US-20090036429-A1 | Hydroxypiperidine Derivatives and Uses Thereof | AVALON PHARMACEUTICALS | 2009-02-05 | — | — | US | disclosed |
| US-20090036429-A1 | Hydroxypiperidine Derivatives and Uses Thereof | AVALON PHARMACEUTICALS | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178066-A1 | Hydroxypiperidine derivatives and uses thereof | HPGDS, HPGD, DPYD | MEN1 3974/4885KMT2A 2446/4885SLC5A7 4329/4885 |
| US-20090036429-A1 | Hydroxypiperidine Derivatives and Uses Thereof | HPGDS, HPGD, DPYD | MEN1 3974/4885KMT2A 2446/4885SLC5A7 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.