Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15348426 | 1.00 | PREP (0.48) | PREPCHRM2CHRM1CHRM3KMT2A | |
| SCHEMBL17066298 | 0.92 | PREP (0.50) | PREPCHRM2CHRM1CHRM3KMT2A | |
| SCHEMBL2706103 | 0.84 | PREP (0.49) | PREPCHRM2CHRM1CHRM3KMT2A | |
| SCHEMBL203928 | 0.83 | PREP (0.47) | PREPCHRM2CHRM1CHRM3KMT2A | |
| SCHEMBL9977163 | 0.83 | PREP (0.47) | PREPCHRM2CHRM1CHRM3KMT2A | |
| SCHEMBL17066736 | 0.82 | PREP (0.42) | PREPCHRM2CHRM1CHRM3KMT2A | |
| SCHEMBL16891276 | 0.82 | PREP (0.43) | PREPCHRM2CHRM1CHRM3KMT2A | |
| SCHEMBL17656300 | 0.80 | PREP (0.41) | PREPCHRM2CHRM1CHRM3KMT2A | |
| SCHEMBL9977370 | 0.79 | PREP (0.43) | PREPCHRM2CHRM1CHRM3KMT2A | |
| SCHEMBL16343910 | 0.79 | PREP (0.39) | PREPCHRM2CHRM1CHRM3KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091532-A1 | HEPATITIS C INHIBITOR COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-04 | — | — | WO | disclosed |