Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15368133 | 0.92 | PREP (0.42) | PREPCHRM2CHRM1CHRM3ALDH1A1 | |
| SCHEMBL9977159 | 0.92 | PREP (0.42) | PREPCHRM2CHRM1CHRM3ALDH1A1 | |
| SCHEMBL2708422 | 0.88 | PREP (0.41) | PREPALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL202883 | 0.88 | PREP (0.41) | PREPALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL18462482 | 0.88 | PREP (0.41) | PREPALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL19339404 | 0.87 | PREP (0.36) | PREPCHRM2CHRM1CHRM3ALDH1A1 | |
| SCHEMBL16891276 | 0.82 | PREP (0.43) | PREPCHRM2CHRM1CHRM3ALDH1A1 | |
| SCHEMBL17066298 | 0.82 | PREP (0.50) | PREPCHRM2CHRM1CHRM3ALDH1A1 | |
| SCHEMBL2709941 | 0.81 | PREP (0.42) | PREPALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL16001579 | 0.81 | PREP (0.42) | PREPALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3002281-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2016-04-06 | — | — | EP | disclosed |