Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 3/20 | 0.44 |
| ▸ | PREP | P48147 | 3/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.41 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 3/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2708612 | 1.00 | HPGDS (0.44) | HPGDSPREPKCNK3KCNK9SSTR3 | |
| SCHEMBL15405790 | 1.00 | HPGDS (0.44) | HPGDSPREPKCNK3KCNK9SSTR3 | |
| SCHEMBL203272 | 1.00 | HPGDS (0.44) | HPGDSPREPKCNK3KCNK9SSTR3 | |
| SCHEMBL18463062 | 1.00 | HPGDS (0.44) | HPGDSPREPKCNK3KCNK9SSTR3 | |
| SCHEMBL202934 | 0.95 | HPGDS (0.47) | HPGDSPREPSSTR3CHRM2CHRM1 | |
| SCHEMBL18462760 | 0.95 | HPGDS (0.47) | HPGDSPREPSSTR3CHRM2CHRM1 | |
| SCHEMBL12999459 | 0.95 | HPGDS (0.47) | HPGDSPREPSSTR3CHRM2CHRM1 | |
| SCHEMBL12328086 | 0.94 | HPGDS (0.45) | HPGDSPREPKCNK3KCNK9SSTR3 | |
| SCHEMBL206037 | 0.91 | HPGDS (0.40) | HPGDSPREPKCNK3KCNK9SSTR3 | |
| SCHEMBL2708494 | 0.91 | HPGDS (0.40) | HPGDSPREPKCNK3KCNK9SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3309157-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2018-04-18 | — | — | EP | disclosed |
| EP-3002281-B1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2017-09-13 | — | — | EP | disclosed |
| WO-2011091532-A1 | HEPATITIS C INHIBITOR COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-04 | — | — | WO | disclosed |