Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10014998 | 0.83 | ESR2 (0.34) | ESR2 | |
| SCHEMBL17365828 | 0.82 | ESR2 (0.31) | ESR2 | |
| SCHEMBL19829669 | 0.81 | ESR2 (0.34) | ESR2 | |
| SCHEMBL10027425 | 0.79 | GRM2 (0.33) | — | |
| SCHEMBL28522291 | 0.79 | TRPV1 (0.31) | ESR2 | |
| SCHEMBL17355617 | 0.76 | ESR2 (0.33) | ESR2 | |
| SCHEMBL20380639 | 0.76 | GRM2 (0.30) | — | |
| SCHEMBL29097673 | 0.76 | ESR2 (0.40) | ESR2MMP2MMP3BACE1 | |
| SCHEMBL10015008 | 0.75 | FLT3 (0.33) | — | |
| SCHEMBL10015001 | 0.75 | CYP11B1 (0.31) | ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2085454-B1 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2011-08-10 | — | — | EP | disclosed |