Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | MVD | P53602 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12438025 | 0.84 | MVD (0.39) | MVD | |
| SCHEMBL12437993 | 0.82 | MVD (0.33) | MVD | |
| SCHEMBL12438019 | 0.80 | MVD (0.31) | MVD | |
| SCHEMBL12438005 | 0.76 | MVD (0.31) | MVD | |
| SCHEMBL12332332 | 0.74 | MVD (0.43) | HMGCRCHRM1TBXA2RADRA1AMVD | |
| SCHEMBL599363 | 0.74 | HMGCR (0.50) | HMGCRCHRM1TBXA2RADRA1AMVD | |
| SCHEMBL18376075 | 0.74 | HMGCR (0.50) | HMGCRCHRM1TBXA2RADRA1AMVD | |
| SCHEMBL1286788 | 0.74 | HMGCR (0.50) | HMGCRCHRM1TBXA2RADRA1AMVD | |
| SCHEMBL12438008 | 0.73 | MVD (0.33) | MVD | |
| SCHEMBL12437992 | 0.70 | BHMT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178043-A1 | Inhibitors of the mevalonate pathway of streptococcus pneumoniae | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178043-A1 | Inhibitors of the mevalonate pathway of streptococcus pneumoniae | FNTA, GGPS1, HMGCR | HMGCR 3/4885CHRM1 4222/4885TBXA2R 3305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.