Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12438466 | 0.85 | IGF1R (0.68) | IGF1R | |
| SCHEMBL12439839 | 0.82 | IGF1R (0.53) | IGF1R | |
| SCHEMBL4558721 | 0.80 | IGF1R (0.78) | IGF1R | |
| SCHEMBL14162124 | 0.78 | IGF1R (0.49) | IGF1RSRC | |
| SCHEMBL14320002 | 0.77 | IGF1R (0.49) | IGF1R | |
| SCHEMBL12438468 | 0.76 | IGF1R (0.67) | IGF1R | |
| SCHEMBL12438114 | 0.74 | IGF1R (0.48) | IGF1RSRC | |
| SCHEMBL14050571 | 0.73 | IGF1R (0.54) | IGF1R | |
| SCHEMBL12438231 | 0.72 | IGF1R (0.42) | IGF1R | |
| SCHEMBL14162070 | 0.71 | IGF1R (0.65) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841760-B1 | PYRIMIDINE DERIVATIVES AS KINASE MODULATORS AND METHOD OF USE | EXELIXIS INC (US) | 2011-08-10 | — | — | EP | disclosed |
| WO-2008005538-A2 | METHODS OF USING IGF1R AND ABL KINASE MODULATORS | EXELIXIS, INC. (US) | 2008-01-10 | — | — | WO | disclosed |