Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 13/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12294896 | 0.93 | MALT1 (0.41) | MALT1DRD4TRPV1 | |
| SCHEMBL9290211 | 0.91 | MALT1 (0.44) | MALT1DRD4TRPV1P2RX7 | |
| SCHEMBL12574860 | 0.91 | MALT1 (0.42) | MALT1TRPV1PHGDH | |
| SCHEMBL10286763 | 0.91 | MALT1 (0.44) | MALT1DRD4TRPV1PHGDH | |
| SCHEMBL9289365 | 0.89 | MALT1 (0.42) | MALT1DRD4 | |
| SCHEMBL13338276 | 0.89 | MALT1 (0.42) | MALT1DRD4TRPV1 | |
| SCHEMBL12574726 | 0.86 | MALT1 (0.41) | MALT1DRD4TRPV1P2RX7 | |
| SCHEMBL13209103 | 0.84 | MALT1 (0.42) | MALT1DRD4TRPV1 | |
| SCHEMBL12574884 | 0.84 | MALT1 (0.42) | MALT1TRPV1PHGDH | |
| SCHEMBL13356325 | 0.84 | MALT1 (0.44) | MALT1DRD4TRPV1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011095462-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-08-11 | — | — | WO | disclosed |
| WO-2011067135-A1 | SPIRO FUSED 1 -AMINO - PIPERIDINE PYRROLIDINE DIONE DERIVATIVES WITH PESTICIDAL ACTIVITY | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-09 | — | — | WO | disclosed |
| WO-2011067131-A1 | SPIROHETEROCYCLIC DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-09 | — | — | WO | disclosed |