SCHEMBL13356325

SCHEMBL13356325

CNC(=O)c1cc(Cl)cc(C)c1NC(=O)C1CC(C)=NN1c1ncccc1Cl

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 12/20 0.44
DRD4 P21917 1/20 0.35
GRM4 Q14833 1/20 0.35
P2RX7 Q99572 2/20 0.34
TRPV1 Q8NER1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13749187 0.94 MALT1 (0.39) MALT1DRD4P2RX7TRPV1
SCHEMBL13961540 0.94 MALT1 (0.41) MALT1P2RX7TRPV1
SCHEMBL9290211 0.93 MALT1 (0.44) MALT1DRD4GRM4P2RX7TRPV1
SCHEMBL1148344 0.92 MALT1 (0.44) MALT1DRD4GRM4TRPV1
SCHEMBL10119182 0.92 MALT1 (0.46) MALT1DRD4TRPV1
SCHEMBL1148395 0.91 MALT1 (0.43) MALT1DRD4GRM4
SCHEMBL13242829 0.90 MALT1 (0.42) MALT1DRD4
SCHEMBL9290237 0.89 MALT1 (0.41) MALT1DRD4TRPV1
SCHEMBL9290198 0.87 MALT1 (0.40) MALT1DRD4P2RX7TRPV1
SCHEMBL3405680 0.86 MALT1 (0.44) MALT1DRD4GRM4P2RX7TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2099785-B1 N-CYANOALKYLANTHRANILAMIDES AS INSECTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2010-05-19 EP disclosed