Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15095996 | 0.88 | IGF1R (0.62) | IGF1RNTRK1 | |
| SCHEMBL11344449 | 0.85 | IGF1R (0.73) | IGF1RNTRK1 | |
| SCHEMBL11340826 | 0.85 | IGF1R (0.69) | IGF1RNTRK1 | |
| SCHEMBL11349278 | 0.85 | IGF1R (0.58) | IGF1RNTRK1 | |
| SCHEMBL11340156 | 0.84 | IGF1R (0.71) | IGF1RNTRK1 | |
| SCHEMBL12439355 | 0.84 | IGF1R (0.57) | IGF1RNTRK1 | |
| SCHEMBL14161939 | 0.84 | IGF1R (0.58) | IGF1RNTRK1 | |
| SCHEMBL15256279 | 0.84 | IGF1R (0.58) | IGF1RNTRK1 | |
| SCHEMBL11344357 | 0.81 | IGF1R (0.67) | IGF1R | |
| SCHEMBL4462307 | 0.80 | IGF1R (0.58) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841760-B1 | PYRIMIDINE DERIVATIVES AS KINASE MODULATORS AND METHOD OF USE | EXELIXIS INC (US) | 2011-08-10 | — | — | EP | disclosed |