Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.47 |
| ▸ | HTR1A | P08908 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 4/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300089 | 0.93 | DRD2 (0.51) | DRD2HTR1AHTR2AHTR2CADRA1A | |
| SCHEMBL1244053 | 0.92 | DRD2 (0.50) | DRD2HTR1AHTR2AHTR2CADRA1A | |
| SCHEMBL1243999 | 0.92 | DRD2 (0.49) | DRD2HTR1AHTR2AHTR2CADRA1A | |
| SCHEMBL1243226 | 0.88 | DRD2 (0.51) | DRD2HTR1AHTR2AHTR2CADRA1A | |
| SCHEMBL293387 | 0.87 | DRD2 (0.53) | DRD2HTR1AHTR2AHTR2CADRA1A | |
| Hydrochloric Acid SCHEMBL4294507 | 0.87 | HTR2A (0.53) | DRD2HTR1AHTR2AHTR2CADRA1A | |
| SCHEMBL12062552 | 0.86 | DRD2 (0.53) | DRD2HTR1AHTR2AHTR2CADRA1A | |
| SCHEMBL1244018 | 0.85 | DRD2 (0.47) | DRD2HTR1AHTR2AHTR2CADRA1A | |
| SCHEMBL294686 | 0.83 | HTR2A (0.53) | DRD2HTR1AHTR2AHTR2CADRA1A | |
| Hydrochloric Acid SCHEMBL293587 | 0.82 | HTR2A (0.51) | DRD2HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919907-B9 | HETEROCYCLIC COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2012-01-18 | — | — | EP | claimed |
| EP-1919907-B1 | HETEROCYCLIC COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2011-02-23 | — | — | EP | claimed |