Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.59 |
| ▸ | HTR2B | P41595 | 3/20 | 0.59 |
| ▸ | HTR2C | P28335 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | HRH1 | P35367 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4485252 | 0.87 | HTR2A (0.47) | HTR2AHTR2BHTR2CCYP3A4CYP1A2 | |
| SCHEMBL28017508 | 0.87 | HTR2A (0.56) | HTR2AHTR2BHTR2CCYP3A4CYP1A2 | |
| SCHEMBL2166742 | 0.86 | HTR2A (0.55) | HTR2AHTR2BHTR2CCYP3A4CYP1A2 | |
| SCHEMBL7612638 | 0.85 | HTR2A (0.66) | HTR2AHTR2BHTR2CCYP3A4CYP1A2 | |
| SCHEMBL14427296 | 0.85 | PPARD (0.44) | HTR2AHTR2BHTR2CCYP3A4CYP1A2 | |
| SCHEMBL3707084 | 0.84 | HTR2A (0.54) | HTR2AHTR2BHTR2CCYP3A4CYP1A2 | |
| SCHEMBL31505846 | 0.84 | HTR2A (0.61) | HTR2AHTR2BHTR2CCYP3A4CYP1A2 | |
| SCHEMBL31283854 | 0.84 | HTR2A (0.54) | HTR2AHTR2BHTR2CCYP3A4CYP1A2 | |
| SCHEMBL26985777 | 0.84 | HTR2A (0.61) | HTR2AHTR2BHTR2CCYP3A4CYP1A2 | |
| SCHEMBL19301233 | 0.84 | HTR2A (0.61) | HTR2AHTR2BHTR2CCYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110177046-A1 | DITHIAZOLIDINE AND THIAZOLIDINE DERIVATIVES AS ANTICANCER AGENTS | BETAGENON AB | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110177046-A1 | DITHIAZOLIDINE AND THIAZOLIDINE DERIVATIVES AS ANTICANCER AGENTS | TK2, FABP4, TXNRD2 | HTR2A 3329/4885HTR2B 4230/4885HTR2C 3484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.