SCHEMBL12440326

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2321937	0.93	MAPK1 (0.40)	ABCG2CYP11B1BCHEIDO1CYP11B2
	SCHEMBL12440325	0.91	PDGFRB (0.40)	ABCG2CYP11B1IDO1CYP11B2ACP1
	SCHEMBL12441225	0.88	NPC1 (0.48)	ABCG2CYP11B1CYP11B2PIM1NPC1
	SCHEMBL12440775	0.88	MAP4K4 (0.41)	CYP11B1IDO1CYP11B2PIM1CYP1A2
	SCHEMBL14141538	0.88	ABCG2 (0.41)	ABCG2CYP11B1BCHEIDO1CYP11B2
	SCHEMBL12440747	0.88	CYP2A6 (0.39)	ABCG2CYP11B1IDO1CYP11B2ACP1
	SCHEMBL2324957	0.86	IDO1 (0.38)	ABCG2CYP11B1BCHEIDO1CYP11B2
	SCHEMBL19791400	0.86	ABCG2 (0.36)	ABCG2CYP11B1BCHEIDO1CYP11B2
	SCHEMBL13834570	0.85	MAP4K4 (0.43)	IDO1TGFBR1
	SCHEMBL13835129	0.85	HCAR2 (0.39)	ABCG2CYP11B1BCHEIDO1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.