SCHEMBL12440747

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2321937	0.90	MAPK1 (0.40)	IDO1F2F10F7F3
	SCHEMBL12440325	0.88	PDGFRB (0.40)	IDO1F2F10F7F3
	SCHEMBL12440326	0.88	ABCG2 (0.40)	CYP2A6IDO1TGFBR1ACP1KDM4E
	SCHEMBL13968337	0.87	CYP2A6 (0.41)	CYP2A6IDO1TGFBR1ABCG2
	SCHEMBL13834933	0.86	IDO1 (0.36)	IDO1F2F10F7F3
	SCHEMBL13834954	0.86	TGFBR1 (0.38)	IDO1TGFBR1ABCG2PRKD3PRKD1
	SCHEMBL2324957	0.85	IDO1 (0.38)	IDO1F2F10F7F3
	SCHEMBL12441208	0.85	HSP90AA1 (0.43)	L3MBTL1KDM4ENPC1RAB9ASMN1; SMN2
	SCHEMBL12440270	0.85	CYP11B1 (0.39)	IDO1TGFBR1KDM4EALDH1A1HPGD
	SCHEMBL12441217	0.85	CNR1 (0.38)	IDO1TGFBR1CYP11B1CYP11B2ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.