Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 3/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2322270 | 0.92 | S1PR1 (0.44) | MAPK1S1PR5S1PR1S1PR4S1PR3 | |
| SCHEMBL10089021 | 0.92 | MAPK1 (0.43) | MAPK1S1PR5S1PR1S1PR4S1PR3 | |
| SCHEMBL10089018 | 0.92 | MAPK1 (0.43) | MAPK1S1PR5S1PR1S1PR4S1PR3 | |
| SCHEMBL13350091 | 0.92 | S1PR5 (0.39) | S1PR5S1PR1S1PR4S1PR3CD274 | |
| Hydrochloric Acid SCHEMBL2385356 | 0.91 | S1PR1 (0.43) | MAPK1S1PR5S1PR1S1PR4S1PR3 | |
| SCHEMBL10089060 | 0.90 | S1PR1 (0.43) | MAPK1S1PR5S1PR1S1PR4S1PR3 | |
| SCHEMBL10088825 | 0.86 | S1PR1 (0.49) | MAPK1S1PR5S1PR1S1PR4S1PR3 | |
| SCHEMBL10310529 | 0.86 | S1PR1 (0.49) | MAPK1S1PR5S1PR1S1PR4S1PR3 | |
| SCHEMBL13349967 | 0.85 | CCR5 (0.40) | — | |
| SCHEMBL13350092 | 0.85 | MAPK1 (0.47) | MAPK1S1PR5S1PR1S1PR4S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2354134-A1 | 2H-CHROMENE COMPOUND AND DERIVATIVE THEREOF | Astellas Pharma Inc. (JP) | 2011-08-10 | — | — | EP | disclosed |