Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 11/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12351034 | 0.89 | AR (0.48) | ARBLMLMNAKDRBACE1 | |
| SCHEMBL12351016 | 0.88 | KDR (0.52) | LMNAMAPTKDRSMN1; SMN2 | |
| SCHEMBL12351022 | 0.86 | NPY2R (0.42) | LMNAMAPTKDRSMN1; SMN2 | |
| SCHEMBL12351029 | 0.85 | AR (0.46) | AR | |
| SCHEMBL2360576 | 0.81 | LMNA (0.61) | LMNAMAPTSMN1; SMN2 | |
| SCHEMBL2358740 | 0.78 | EPHX2 (0.43) | SMN1; SMN2 | |
| SCHEMBL2360538 | 0.77 | P2RX4 (0.50) | LMNAMAPTKDRSMN1; SMN2 | |
| SCHEMBL2360243 | 0.77 | EPHX1 (0.45) | LMNAMAPT | |
| SCHEMBL12351017 | 0.77 | IDO1 (0.40) | MAPT | |
| SCHEMBL2359981 | 0.76 | LMNA (0.41) | LMNAMAPTKDRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094953-A1 | COMPOUNDS FOR THE TREATMENT AND PREVENTION OF INFLUENZA | F. HOFFMANN-LA ROCHE AG (CH) | 2011-08-11 | — | — | WO | disclosed |
| WO-2011095576-A1 | COMPOUNDS FOR THE TREATMENT AND PREVENTION OF INFLUENZA | F. HOFFMANN-LA ROCHE AG (CH) | 2011-08-11 | — | — | WO | disclosed |