Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1243340 | 0.99 | — | — | |
| SCHEMBL731326 | 0.97 | MEN1 (0.32) | MEN1KMT2AALDH1A1POLB | |
| SCHEMBL731075 | 0.96 | — | — | |
| SCHEMBL731467 | 0.80 | EPHX1 (0.34) | — | |
| SCHEMBL1244090 | 0.75 | USP2 (0.36) | ALDH1A1 | |
| SCHEMBL1243338 | 0.74 | USP2 (0.34) | ALDH1A1 | |
| SCHEMBL731325 | 0.73 | USP2 (0.33) | ALDH1A1 | |
| SCHEMBL4662070 | 0.73 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1POLB | |
| SCHEMBL4722847 | 0.71 | ALDH1A1 (0.44) | KMT2AALDH1A1 | |
| SCHEMBL28786559 | 0.71 | ALDH1A1 (0.34) | MEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028494-A1 | HCV NS3 Protease Inhibitors | MERCK SHARP & DOHME LLC | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028494-A1 | HCV NS3 Protease Inhibitors | HAVCR2, GTF3C3, CTSC | MEN1 4761/4885KMT2A 3629/4885ALDH1A1 1199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.