Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13156122 | 1.00 | PPARA (0.57) | PPARAPPARGKCNH2PPARDMAOA | |
| SCHEMBL3113325 | 0.86 | NPC1 (0.58) | PPARAPPARGKCNH2PPARDMAOB | |
| SCHEMBL14173881 | 0.84 | KCNH2 (0.65) | PPARAKCNH2PPARDMAOAMAOB | |
| SCHEMBL14376420 | 0.83 | PPARA (0.64) | PPARAPPARGPPARDCA1CA2 | |
| SCHEMBL7987761 | 0.83 | ALDH1A1 (0.55) | PPARAPPARGKCNH2PPARDCA1 | |
| Hydrochloric Acid SCHEMBL27900832 | 0.82 | KCNH2 (0.62) | PPARAKCNH2PPARDMAOAMAOB | |
| SCHEMBL7987772 | 0.82 | PPARA (0.56) | PPARAPPARGKCNH2PPARDCA1 | |
| SCHEMBL7987719 | 0.82 | PPARA (0.59) | PPARAPPARGPPARDMAOAMAOB | |
| SCHEMBL7155846 | 0.82 | FFAR1 (0.68) | PPARAPPARGPPARDL3MBTL1FFAR1 | |
| SCHEMBL7987736 | 0.81 | PPARA (0.58) | PPARAPPARGPPARDMAOBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011098801-A1 | INFLAMMATORY DISEASE TREATMENT | PULMAGEN THERAPEUTICS (INFLAMMATION) LIMITED (GB) | 2011-08-18 | — | — | WO | disclosed |