SCHEMBL1244293

SCHEMBL1244293

O=C(O)C(C(=O)O)c1ccccc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.50
ACP3 P15309 1/20 0.48
ALDH1A1 P00352 1/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
CXCL8 P10145 1/20 0.45
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
IDO1 P14902 2/20 0.42
TDO2 P48775 2/20 0.42
IDO2 Q6ZQW0 2/20 0.42
IGFBP3 P17936 1/20 0.42
CASP1 P29466 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.39
TSHR P16473 2/20 0.39
LMNA P02545 1/20 0.39
AOC3 Q16853 1/20 0.39
ADRB2 P07550 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL8953448 0.96 SRC (0.46) SRCACP3ALDH1A1MEN1KMT2A
SCHEMBL8953446 0.94 SRC (0.45) SRCACP3ALDH1A1MEN1KMT2A
SCHEMBL5861540 0.88 SRC (0.43) SRCACP3ALDH1A1MEN1KMT2A
SCHEMBL8209137 0.88 CXCL8 (0.44) SRCACP3ALDH1A1MEN1KMT2A
SCHEMBL8536416 0.88 SRC (0.43) SRCACP3ALDH1A1MEN1KMT2A
Benzoic Acid SCHEMBL8953221 0.86 TSHR (0.47) SRCACP3ALDH1A1MEN1KMT2A
SCHEMBL26136641 0.83 SRC (0.62) SRCALDH1A1CES2CES1CYP1A2
SCHEMBL9518776 0.82 CXCL8 (0.47) ACP3ALDH1A1KMT2ACXCL8CES2
SCHEMBL24733 0.80 LMNA (0.52) ACP3ALDH1A1MEN1KMT2ACXCL8
SCHEMBL24732 0.80 LMNA (0.52) ACP3ALDH1A1MEN1KMT2ACXCL8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2467459-A1 ANTIWEAR COMPOSITION AND METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE The Lubrizol Corporation (US) 2012-06-27 EP claimed
WO-2011022347-A1 ANTIWEAR COMPOSITION AND METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE THE LUBRIZOL CORPORATION (US) 2011-02-24 WO claimed
EP-0680976-B1 Process for producing ethylene copolymers HUELS CHEMISCHE WERKE AG (DE) 1997-12-29 EP claimed
US-5502125-A Process for preparing ethylene copolymers HUELS AKTIENGESELLSCHAFT (DE) 1996-03-26 US claimed
EP-2507349-B1 STABILIZED BLENDS CONTAINING FRICTION MODIFIERS LUBRIZOL CORP (US) 2020-06-10 EP disclosed
US-10190071-B2 Stabilized blends containing friction modifiers THE LUBRIZOL CORPORATION (US) 2019-01-29 US disclosed
WO-2017097870-A1 SUBSTITUTED MALONIC ACID AMIDES AS INSECTICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-06-15 WO disclosed
US-9631160-B2 Stabilized blends containing friction modifiers THE LUBRIZOL CORPORATION (US) 2017-04-25 US disclosed
US-20170058230-A1 STABILIZED BLENDS CONTAINING FRICTION MODIFIERS LUBRIZOL CORP (US) 2017-03-02 US disclosed
US-9540581-B2 Stabilized blends containing friction modifiers THE LUBRIZOL CORPORATION (US) 2017-01-10 US disclosed
US-9528067-B2 Stabilized blends containing friction modifiers THE LUBRIZOL CORPORATION (US) 2016-12-27 US disclosed
US-20160122683-A1 SYNERGISTIC ADDITIVE COMBINATION FOR INDUSTRIAL GEAR OILS THE LUBRIZOL CORPORATION (US) 2016-05-05 US disclosed
EP-1140784-A2 ION CHANNEL MODULATING AGENTS NEUROSEARCH A/S (DK) 2001-10-10 EP disclosed
US-6255342-B1 PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-07-03 US disclosed
US-6114374-A USE AS PESTICIDES SUCH AS INSECTICIDES AND ACARICIDES; WELL TOLERATED BY CROPS BAYER AKTIENGESELLSCHAFT (DE) 2000-09-05 US disclosed
WO-2000037422-A2 ION CHANNEL MODULATING AGENTS NEUROSEARCH A/S (DK) 2000-06-29 WO disclosed
CN-1232450-A 2-and 2, 5-substituted phenyl keto-enols BAYER AG (DE) 1999-10-20 CN disclosed
EP-0915846-A2 2- AND 2,5-SUBSTITUTED PHENYLKETOENOLS BAYER AG (DE) 1999-05-19 EP disclosed
WO-1998005638-A2 2- AND 2,5-SUBSTITUTED PHENYLKETOENOLS BAYER AKTIENGESELLSCHAFT (DE) 1998-02-12 WO disclosed
US-5521138-A COLOR DEVELOPMENT AND CRYSTALLIZATION RICOH COMPANY, LTD. (JP) 1996-05-28 US disclosed