Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K11 | Q16584 | 14/20 | 0.90 |
| ▸ | MAP3K9 | P80192 | 12/20 | 0.90 |
| ▸ | MAP3K10 | Q02779 | 8/20 | 0.90 |
| ▸ | KDR | P35968 | 4/20 | 0.90 |
| ▸ | FLT1 | P17948 | 1/20 | 0.90 |
| ▸ | FLT4 | P35916 | 1/20 | 0.90 |
| ▸ | DLK1 | P80370 | 1/20 | 0.90 |
| ▸ | NTRK1 | P04629 | 8/20 | 0.84 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.67 |
| ▸ | PRKCG | P05129 | 3/20 | 0.67 |
| ▸ | PRKCB | P05771 | 3/20 | 0.67 |
| ▸ | PRKCA | P17252 | 3/20 | 0.67 |
| ▸ | PRKCH | P24723 | 3/20 | 0.67 |
| ▸ | PRKCI | P41743 | 3/20 | 0.67 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.67 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.67 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.67 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.67 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.67 |
| ▸ | MYLK | Q15746 | 3/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cep-1347 SCHEMBL8263437 | 0.95 | MAP3K11 (1.00) | MAP3K11MAP3K9MAP3K10KDRFLT1 | |
| Cep-1347 SCHEMBL29381680 | 0.95 | MAP3K11 (1.00) | MAP3K11MAP3K9MAP3K10KDRFLT1 | |
| Cep-1347 SCHEMBL12047710 | 0.95 | MAP3K11 (1.00) | MAP3K11MAP3K9MAP3K10KDRFLT1 | |
| Cep-1347 SCHEMBL30198505 | 0.95 | MAP3K11 (1.00) | MAP3K11MAP3K9MAP3K10KDRFLT1 | |
| SCHEMBL13179116 | 0.92 | MAP3K11 (0.78) | MAP3K11MAP3K9MAP3K10KDRFLT1 | |
| SCHEMBL13142263 | 0.92 | MAP3K11 (0.93) | MAP3K11MAP3K9MAP3K10KDRFLT1 | |
| SCHEMBL13140134 | 0.92 | MAP3K11 (0.93) | MAP3K11MAP3K9MAP3K10KDRFLT1 | |
| SCHEMBL13264035 | 0.91 | MAP3K11 (0.73) | MAP3K11MAP3K9MAP3K10KDRFLT1 | |
| SCHEMBL5964631 | 0.88 | MAP3K11 (0.86) | MAP3K11MAP3K9MAP3K10KDRFLT1 | |
| SCHEMBL15289975 | 0.86 | MAP3K11 (1.00) | MAP3K11MAP3K9MAP3K10KDRFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685137-B1 | PARTICLE-FORMING COMPOSITIONS CONTAINING FUSED PYRROLOCARBAZOLES | CEPHALON INC (US) | 2011-08-17 | — | — | EP | disclosed |