Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14294336 | 0.81 | LMNA (0.52) | LMNAGAAHPGDTSHRKMT2A | |
| SCHEMBL1543126 | 0.78 | LMNA (0.52) | LMNAGAAHPGDTSHRKMT2A | |
| SCHEMBL2107124 | 0.78 | LMNA (0.52) | LMNAGAAHPGDTSHRKMT2A | |
| SCHEMBL2223682 | 0.78 | LMNA (0.52) | LMNAGAAHPGDTSHRKMT2A | |
| SCHEMBL2224843 | 0.78 | LMNA (0.59) | LMNAGAAHPGDTSHRKMT2A | |
| SCHEMBL13153218 | 0.77 | LMNA (0.49) | LMNAGAAHPGDTSHRKMT2A | |
| SCHEMBL2223461 | 0.76 | LMNA (0.54) | LMNAGAAHPGDTSHRKMT2A | |
| SCHEMBL4140061 | 0.76 | LMNA (0.48) | LMNAGAAHPGDTSHRKMT2A | |
| SCHEMBL2222314 | 0.75 | LMNA (0.50) | LMNAGAAHPGDTSHRKMT2A | |
| SCHEMBL2221076 | 0.74 | LMNA (0.49) | LMNAGAAHPGDTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786913-B1 | METHOD FOR THE PRODUCTION OF DIARYLCYCLOALKYL DERIVATIVES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-08-17 | — | — | EP | disclosed |