Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OSBP | P22059 | 1/20 | 0.33 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14945240 | 1.00 | OSBP (0.33) | OSBPOSBP2TSHR | |
| SCHEMBL8177417 | 0.93 | OSBP (0.34) | OSBPOSBP2 | |
| SCHEMBL8710847 | 0.93 | OSBP (0.34) | OSBPOSBP2 | |
| SCHEMBL27139803 | 0.87 | OSBP (0.34) | OSBPOSBP2 | |
| SCHEMBL14511538 | 0.87 | OSBP (0.31) | OSBPOSBP2 | |
| SCHEMBL1892052 | 0.81 | TSHR (0.36) | OSBPOSBP2TSHR | |
| SCHEMBL26906219 | 0.81 | TSHR (0.36) | OSBPOSBP2TSHR | |
| SCHEMBL9785228 | 0.80 | OSBP (0.33) | OSBPOSBP2 | |
| SCHEMBL2330280 | 0.78 | OSBP (0.32) | OSBPOSBP2 | |
| SCHEMBL4078008 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786913-B1 | METHOD FOR THE PRODUCTION OF DIARYLCYCLOALKYL DERIVATIVES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-08-17 | — | — | EP | disclosed |
| US-7803950-B2 | Method for the production of diarylcycloalkyl derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2010-09-28 | — | — | US | disclosed |
| US-7803950-B2 | Method for the production of diarylcycloalkyl derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2010-09-28 | — | — | US | disclosed |
| US-20080051583-A1 | NOVEL INTERMEDIATE COMPOUNDS USEFUL IN THE PRODUCTION OF DIARYLCYCLOALKYL DERIVATIVES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-02-28 | — | — | US | disclosed |
| US-20080051583-A1 | NOVEL INTERMEDIATE COMPOUNDS USEFUL IN THE PRODUCTION OF DIARYLCYCLOALKYL DERIVATIVES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-02-28 | — | — | US | disclosed |
| US-20070197614-A1 | METHOD FOR THE PRODUCTION OF DIARYLCYCLOALKYL DERIVATIVES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-08-23 | — | — | US | disclosed |
| US-20070197614-A1 | METHOD FOR THE PRODUCTION OF DIARYLCYCLOALKYL DERIVATIVES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051583-A1 | NOVEL INTERMEDIATE COMPOUNDS USEFUL IN THE PRODUCTION OF DIARYLCYCLOALKYL DERIVATIVES | PPARG, PPARD, PPARA | OSBP 1189/4885OSBP2 2436/4885TSHR 935/4885 |
| US-20070197614-A1 | METHOD FOR THE PRODUCTION OF DIARYLCYCLOALKYL DERIVATIVES | PPARA, PPARD, PPARG | OSBP 1000/4885OSBP2 2243/4885TSHR 602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.