Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OSBP | P22059 | 1/20 | 0.34 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8177417 | 1.00 | OSBP (0.34) | OSBPOSBP2MEN1KMT2A | |
| SCHEMBL14945240 | 0.93 | OSBP (0.33) | OSBPOSBP2 | |
| SCHEMBL12445018 | 0.93 | OSBP (0.33) | OSBPOSBP2 | |
| SCHEMBL27139803 | 0.90 | OSBP (0.34) | OSBPOSBP2MEN1KMT2A | |
| SCHEMBL26906219 | 0.88 | TSHR (0.36) | OSBPOSBP2MEN1KMT2A | |
| SCHEMBL1892052 | 0.88 | TSHR (0.36) | OSBPOSBP2MEN1KMT2A | |
| SCHEMBL16411045 | 0.83 | OSBP (0.33) | OSBPOSBP2MEN1KMT2A | |
| SCHEMBL14511538 | 0.82 | OSBP (0.31) | OSBPOSBP2 | |
| SCHEMBL9785228 | 0.79 | OSBP (0.33) | OSBPOSBP2MEN1KMT2A | |
| SCHEMBL3488642 | 0.79 | MEN1 (0.30) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693054-B1 | CYCLOALKYLHYDROXYUREAS AND THEIR USE AS LIPOXYGENASE INHIBITORS | PFIZER (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5681858-A | Cycloalkyl hydroxyureas | PFIZER INC. (US) | 1997-10-28 | — | — | US | disclosed |