Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 2/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL728878 | 1.00 | ATM (0.42) | ATMHCAR2LMNAMAPK1HTT | |
| SCHEMBL2672114 | 0.88 | ATM (0.46) | ATMHCAR2LMNAALDH1A1KDM4E | |
| SCHEMBL36569 | 0.88 | ATM (0.46) | ATMHCAR2LMNAALDH1A1KDM4E | |
| SCHEMBL28089518 | 0.87 | ATM (0.44) | ATMHCAR2LMNAALDH1A1KDM4E | |
| SCHEMBL107869 | 0.86 | ATM (0.55) | ATMHCAR2LMNAALDH1A1KDM4E | |
| SCHEMBL108806 | 0.86 | ATM (0.55) | ATMHCAR2LMNAALDH1A1KDM4E | |
| SCHEMBL107870 | 0.86 | ATM (0.55) | ATMHCAR2LMNAALDH1A1KDM4E | |
| SCHEMBL28427011 | 0.86 | ATM (0.41) | ATMHCAR2LMNAMAPK1HTT | |
| SCHEMBL28230711 | 0.85 | ATM (0.43) | ATMHCAR2LMNAALDH1A1KDM4E | |
| SCHEMBL1904077 | 0.84 | ATM (0.53) | ATMHCAR2LMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107743492-B | Process for preparing acryloxysilanes | 美国陶氏有机硅公司 | 2020-07-17 | — | — | CN | claimed |
| CN-107743492-B | Process for preparing acryloxysilanes | 美国陶氏有机硅公司 | 2020-07-17 | — | — | CN | disclosed |
| US-9493615-B2 | Organopolysiloxanes containing an unsaturated group | DOW CORNING CORPORATION (US) | 2016-11-15 | — | — | US | disclosed |
| US-9388265-B2 | Method for producing silyl-functionalized polyolefins and silyl-functionalized polyolefins with silyl monomer incorporation | DOW CORNING CORPORATION (US) | 2016-07-12 | — | — | US | disclosed |
| US-20140031487-A1 | EPOXIDISED ELASTOMER COMPOSITIONS MODIFIED BY SILANES | RHODIA OPERATION (FR) | 2014-01-30 | — | — | US | disclosed |
| US-8476375-B2 | Polymers modified by silanes | DOW CORNING CORPORATION (US) | 2013-07-02 | — | — | US | disclosed |
| US-20120283362-A1 | ORGANOPOLYSILOXANES CONTAINING AN UNSATURATED GROUP | DOW SILICONES CORPORATION | 2012-11-08 | — | — | US | disclosed |
| US-20110178198-A1 | POLYMERS MODIFIED BY SILANES | DOW SILICONES CORPORATION | 2011-07-21 | — | — | US | disclosed |