SCHEMBL728878

SCHEMBL728878

CC=CC=CC(=O)OCCC[Si](OC)(OC)OC

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.42
HCAR2 Q8TDS4 4/20 0.38
LMNA P02545 2/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
AKR1B10 O60218 4/20 0.33
AKR1B1 P15121 4/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 2/20 0.33
HPGD P15428 1/20 0.33
CYP3A4 P08684 1/20 0.32
MET P08581 2/20 0.30
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12445250 1.00 ATM (0.42) ATMHCAR2LMNAMAPK1HTT
SCHEMBL2672114 0.88 ATM (0.46) ATMHCAR2LMNAALDH1A1KDM4E
SCHEMBL36569 0.88 ATM (0.46) ATMHCAR2LMNAALDH1A1KDM4E
SCHEMBL28089518 0.87 ATM (0.44) ATMHCAR2LMNAALDH1A1KDM4E
SCHEMBL107869 0.86 ATM (0.55) ATMHCAR2LMNAALDH1A1KDM4E
SCHEMBL108806 0.86 ATM (0.55) ATMHCAR2LMNAALDH1A1KDM4E
SCHEMBL107870 0.86 ATM (0.55) ATMHCAR2LMNAALDH1A1KDM4E
SCHEMBL28427011 0.86 ATM (0.41) ATMHCAR2LMNAMAPK1HTT
SCHEMBL28230711 0.85 ATM (0.43) ATMHCAR2LMNAALDH1A1KDM4E
SCHEMBL1904077 0.84 ATM (0.53) ATMHCAR2LMNAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3310792-B1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORP (US) 2021-07-21 EP claimed
EP-3310793-B1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORP (US) 2021-06-09 EP claimed
US-10273254-B2 Process for preparing an acryloyloxysilane DOW CORNING CORPORATION (US) 2019-04-30 US claimed
US-10246473-B2 Process for preparing an acryloyloxysilane DOW CORNING CORPORATION (US) 2019-04-02 US claimed
EP-2294101-B1 POLYMERS MODIFIED BY SILANES DOW SILICONES CORP (US) 2018-10-17 EP claimed
US-20180155371-A1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORPORATION 2018-06-07 US claimed
US-20180134734-A1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORPORATION 2018-05-17 US claimed
EP-3310792-A1 PROCESS FOR PREPARING AN ACRYLOYLOYLOXYSILANE Dow Corning Corporation (US) 2018-04-25 EP claimed
EP-3310793-A1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE Dow Corning Corporation (US) 2018-04-25 EP claimed
WO-2016205648-A1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW CORNING CORPORATION (US) 2016-12-22 WO claimed
WO-2016205642-A1 PROCESS FOR PREPARING AN ACRYLOYLOYLOXYSILANE DOW CORNING CORPORATION (US) 2016-12-22 WO claimed
US-8476375-B2 Polymers modified by silanes DOW CORNING CORPORATION (US) 2013-07-02 US claimed
JP-2011526313-A 2011-10-06 JP claimed
EP-2294101-A1 POLYMERS MODIFIED BY SILANES Dow Corning Corporation (US) 2011-03-16 EP claimed
WO-2010000479-A1 POLYMERS MODIFIED BY SILANES DOW CORNING CORPORATION (US) 2010-01-07 WO claimed
EP-2665756-B1 METHOD FOR PRODUCING SILYL-FUNCTIONALIZED POLYOLEFINS AND SILYL-FUNCTIONALIZED POLYOLEFINS WITH SILYL MONOMER INCORPORATION DOW SILICONES CORP (US) 2022-03-30 EP disclosed
EP-3310792-B1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORP (US) 2021-07-21 EP disclosed
US-20110178198-A1 POLYMERS MODIFIED BY SILANES DOW SILICONES CORPORATION 2011-07-21 US disclosed
EP-2294101-A1 POLYMERS MODIFIED BY SILANES Dow Corning Corporation (US) 2011-03-16 EP disclosed
WO-2010000479-A1 POLYMERS MODIFIED BY SILANES DOW CORNING CORPORATION (US) 2010-01-07 WO disclosed