Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1478647 | 0.96 | F10 (0.46) | F10ALDH1A1MEN1ALOX12APOBEC3A | |
| SCHEMBL1479417 | 0.93 | F10 (0.45) | F10ALDH1A1MEN1ALOX12APOBEC3A | |
| SCHEMBL1479333 | 0.91 | F10 (0.45) | F10ALDH1A1MEN1ALOX12APOBEC3A | |
| SCHEMBL1479106 | 0.91 | F10 (0.41) | F10ALDH1A1MEN1ALOX12APOBEC3A | |
| SCHEMBL1479443 | 0.91 | F10 (0.45) | F10ALDH1A1MEN1ALOX12APOBEC3A | |
| SCHEMBL1481821 | 0.91 | MEN1 (0.43) | F10ALDH1A1MEN1ALOX12APOBEC3A | |
| SCHEMBL1479476 | 0.91 | ALDH1A1 (0.51) | ALDH1A1MEN1ALOX12APOBEC3AKMT2A | |
| SCHEMBL1479965 | 0.90 | MEN1 (0.43) | F10ALDH1A1MEN1ALOX12APOBEC3A | |
| SCHEMBL1479976 | 0.90 | F10 (0.46) | F10ALDH1A1MEN1ALOX12APOBEC3A | |
| SCHEMBL1479223 | 0.89 | F10 (0.47) | F10ALDH1A1MEN1ALOX12APOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771441-B1 | NOVEL CARBOXAMIDES FOR USE AS XA INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2011-08-17 | — | — | EP | disclosed |