Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2333389 | 1.00 | KMT2A (0.51) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL2340415 | 1.00 | KMT2A (0.51) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL2332761 | 0.93 | KMT2A (0.52) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL2338681 | 0.93 | KMT2A (0.52) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL2333223 | 0.92 | KMT2A (0.51) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL2333228 | 0.92 | KMT2A (0.51) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL2336824 | 0.90 | KMT2A (0.48) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL2340165 | 0.90 | KMT2A (0.48) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL12449313 | 0.90 | KMT2A (0.48) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL6653644 | 0.90 | KMT2A (0.51) | KMT2AMEN1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465882-B1 | HETROCYCLIC MODULATORS OF NUCLEAR RECEPTORS | X CEPTOR THERAPEUTICS INC (US) | 2011-08-24 | — | — | EP | disclosed |