Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.38 |
| ▸ | ACP1 | P24666 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2333389 | 0.90 | KMT2A (0.51) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL12448461 | 0.90 | KMT2A (0.51) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL2340415 | 0.90 | KMT2A (0.51) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL2332761 | 0.88 | KMT2A (0.52) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL2338681 | 0.88 | KMT2A (0.52) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL2333393 | 0.87 | KMT2A (0.51) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL2342317 | 0.87 | KMT2A (0.51) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL12447993 | 0.87 | KMT2A (0.51) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL2340814 | 0.87 | KMT2A (0.57) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL2340817 | 0.87 | KMT2A (0.57) | KMT2AMEN1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003060078-A9 | HETEROCYCLIC MODULATORS OF NUCLEAR RECEPTORS | X CEPTOR THERAPEUTICS INC (US) | 2004-02-19 | — | — | WO | disclosed |