Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | STAT1 | P42224 | 1/20 | 0.56 |
| ▸ | TOP1 | P11387 | 2/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1863470 | 0.91 | STAT3 (0.59) | STAT3STAT1TOP1CHEK2HPSE | |
| SCHEMBL3995625 | 0.84 | STAT3 (0.78) | STAT3STAT1TOP1MEN1KMT2A | |
| SCHEMBL7257328 | 0.82 | STAT3 (0.56) | STAT3STAT1TOP1MEN1KMT2A | |
| SCHEMBL10100940 | 0.82 | STAT3 (0.64) | STAT3STAT1TOP1MEN1KMT2A | |
| SCHEMBL7258061 | 0.82 | STAT3 (0.64) | STAT3STAT1TOP1MEN1KMT2A | |
| SCHEMBL30372046 | 0.82 | STAT3 (0.64) | STAT3STAT1TOP1MEN1KMT2A | |
| SCHEMBL27992764 | 0.81 | STAT3 (0.63) | STAT3STAT1TOP1MEN1KMT2A | |
| SCHEMBL29823978 | 0.81 | STAT3 (0.62) | STAT3STAT1TOP1MEN1KMT2A | |
| Aniline SCHEMBL28730723 | 0.80 | STAT3 (0.78) | STAT3STAT1TOP1NPC1ALDH1A1 | |
| SCHEMBL14818489 | 0.78 | STAT3 (0.56) | STAT3STAT1TOP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558616-B2 | MESO-SUBSTITUTED PORPHYRINS | MOLTENI & C (IT) | 2011-08-24 | — | — | EP | disclosed |