Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 19/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL389101 | 0.88 | GPR119 (0.70) | GPR119CYP2C9KCNH2 | |
| SCHEMBL1245445 | 0.79 | GPR119 (0.53) | GPR119CYP2C9KCNH2 | |
| SCHEMBL389403 | 0.75 | GPR119 (0.70) | GPR119CYP2C9KCNH2 | |
| SCHEMBL391674 | 0.73 | GPR119 (0.72) | GPR119CYP2C9KCNH2 | |
| SCHEMBL389698 | 0.73 | GPR119 (0.70) | GPR119CYP2C9KCNH2 | |
| SCHEMBL389080 | 0.73 | GPR119 (0.70) | GPR119CYP2C9KCNH2 | |
| SCHEMBL390642 | 0.73 | GPR119 (0.72) | GPR119CYP2C9KCNH2 | |
| SCHEMBL13404782 | 0.73 | GPR119 (0.71) | GPR119CYP2C9KCNH2 | |
| SCHEMBL390160 | 0.73 | GPR119 (0.69) | GPR119CYP2C9KCNH2 | |
| SCHEMBL389429 | 0.73 | GPR119 (0.69) | GPR119CYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2287165-A2 | Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto | Arena Pharmaceuticals, Inc. (US) | 2011-02-23 | — | — | EP | disclosed |