SCHEMBL12450340

SCHEMBL12450340

c1ccc2sc(-c3ccc4c5ccccc5c5ccccc5c4c3)nc2c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 6/20 0.60
RAB9A P51151 9/20 0.60
KDM4E B2RXH2 6/20 0.60
MAPT P10636 6/20 0.60
NPC1 O15118 5/20 0.60
ALDH1A1 P00352 4/20 0.60
LMNA P02545 3/20 0.60
GLA P06280 3/20 0.60
GAA P10253 3/20 0.60
MMP9 P14780 1/20 0.60
MMP8 P22894 1/20 0.60
SMN1; SMN2 Q16637 5/20 0.59
NFKB1 P19838 4/20 0.59
NFKB2 Q00653 4/20 0.59
RELA Q04206 4/20 0.59
TP53 P04637 2/20 0.59
HSD17B10 Q99714 2/20 0.59
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
POLB P06746 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26535822 0.94 RAB9A (0.61) APPRAB9AKDM4EMAPTNPC1
SCHEMBL27258765 0.94 RAB9A (0.61) APPRAB9AKDM4EMAPTNPC1
SCHEMBL26535825 0.94 RAB9A (0.61) APPRAB9AKDM4EMAPTNPC1
SCHEMBL26535744 0.94 RAB9A (0.61) APPRAB9AKDM4EMAPTNPC1
SCHEMBL17343947 0.93 APP (0.61) APPRAB9AKDM4EMAPTNPC1
SCHEMBL17343963 0.93 APP (0.61) APPRAB9AKDM4EMAPTNPC1
SCHEMBL26535965 0.92 RAB9A (0.60) APPRAB9AKDM4EMAPTNPC1
SCHEMBL26535962 0.92 RAB9A (0.60) APPRAB9AKDM4EMAPTNPC1
SCHEMBL17343993 0.91 RAB9A (0.58) APPRAB9AKDM4EMAPTNPC1
SCHEMBL26535967 0.90 RAB9A (0.57) APPRAB9AKDM4EMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9522895-B2 Organometallic complexes which emit in the red to green spectral region and their use in OLEDs UDC IRELAND LIMITED (IE) 2016-12-20 US disclosed
US-9522895-B2 Organometallic complexes which emit in the red to green spectral region and their use in OLEDs UDC IRELAND LIMITED (IE) 2016-12-20 US disclosed
US-20150364694-A1 ORGANIC COMPOUND, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE CHEIL INDUSTRIES INC. (KR) 2015-12-17 US disclosed
US-20150364694-A1 ORGANIC COMPOUND, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE CHEIL INDUSTRIES INC. (KR) 2015-12-17 US disclosed
US-20130231489-A1 NOVEL ORGANOMETALLIC COMPLEXES WHICH EMIT IN THE RED TO GREEN SPECTRAL REGION AND THEIR USE IN OLEDS BASF SE (DE) 2013-09-05 US disclosed
US-20130231489-A1 NOVEL ORGANOMETALLIC COMPLEXES WHICH EMIT IN THE RED TO GREEN SPECTRAL REGION AND THEIR USE IN OLEDS BASF SE (DE) 2013-09-05 US disclosed
US-8455112-B2 Organometallic complexes which emit in the red to green spectral region and their use in OLEDs BASF SE (DE) 2013-06-04 US disclosed
US-8455112-B2 Organometallic complexes which emit in the red to green spectral region and their use in OLEDs BASF SE (DE) 2013-06-04 US disclosed
EP-2134807-B1 IRIDIUM-TRIPHENYLENE COMPLEXES AND THEIR USE IN OLEDS BASF SE (DE) 2011-08-31 EP disclosed
US-20100127215-A1 NOVEL ORGANOMETALLIC COMPLEXES WHICH EMIT IN THE RED TO GREEN SPECTRAL REGION AND THEIR USE IN OLEDS BASF SE (DE) 2010-05-27 US disclosed
US-20100127215-A1 NOVEL ORGANOMETALLIC COMPLEXES WHICH EMIT IN THE RED TO GREEN SPECTRAL REGION AND THEIR USE IN OLEDS BASF SE (DE) 2010-05-27 US disclosed
US-20100109515-A1 OLED WITH METAL COMPLEXES HAVING A HIGH QUANTUM EFFICIENCY KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2010-05-06 US disclosed
US-20100109515-A1 OLED WITH METAL COMPLEXES HAVING A HIGH QUANTUM EFFICIENCY KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2010-05-06 US disclosed
WO-2008122943-A1 OLED WITH METAL COMPLEXES HAVING A HIGH QUANTUM EFFICIENCY PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH (DE) 2008-10-16 WO disclosed
WO-2008122603-A2 IRIDIUM-TRIPHENYLENE COMPLEXES AND THEIR USE IN OLEDS BASF SE (DE) 2008-10-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130231489-A1 NOVEL ORGANOMETALLIC COMPLEXES WHICH EMIT IN THE RED TO GREEN SPECTRAL REGION AND THEIR USE IN OLEDS OCIAD1, ORC3, OCIAD2 APP 3506/4885RAB9A 3011/4885KDM4E 4436/4885
US-20100127215-A1 NOVEL ORGANOMETALLIC COMPLEXES WHICH EMIT IN THE RED TO GREEN SPECTRAL REGION AND THEIR USE IN OLEDS OCIAD1, ORC3, OCIAD2 APP 3506/4885RAB9A 3011/4885KDM4E 4436/4885
US-20150364694-A1 ORGANIC COMPOUND, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE OCIAD1, OR10J3, OR51E2 APP 2004/4885RAB9A 3208/4885KDM4E 3980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.