Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14351424 | 0.80 | CYP2C9 (0.37) | CYP2C9CYP2C19TSHRMTORHRH4 | |
| SCHEMBL8738612 | 0.76 | — | — | |
| SCHEMBL2439432 | 0.75 | — | — | |
| SCHEMBL1245091 | 0.74 | CYP2C9 (0.47) | CYP2C9CYP2C19TSHRMTORHRH4 | |
| SCHEMBL17014704 | 0.72 | CYP2C9 (0.48) | CYP2C9CYP2C19TSHRMTORHRH4 | |
| SCHEMBL29391472 | 0.71 | CYP2C9 (0.44) | CYP2C9CYP2C19TSHRMTORHRH4 | |
| SCHEMBL5956451 | 0.71 | — | — | |
| SCHEMBL7283194 | 0.71 | GPR119 (0.33) | — | |
| SCHEMBL14351443 | 0.70 | CYP2C9 (0.43) | CYP2C9CYP2C19TSHRMTORHRH4 | |
| SCHEMBL25475209 | 0.69 | TSHR (0.42) | CYP2C9CYP2C19TSHRMTORHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011014520-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-02-03 | — | — | WO | claimed |
| WO-2011014520-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-02-03 | — | — | WO | disclosed |