SCHEMBL1245101

SCHEMBL1245101

CC(C)NCC(O)COCCC[Si](C)(C)CC[Si](C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ADRB1 P08588 4/20 0.42
ADRB2 P07550 3/20 0.42
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
CYP2D6 P10635 2/20 0.37
ADRB3 P13945 1/20 0.37
PTGS1 P23219 1/20 0.36
SLC6A2 P23975 1/20 0.36
HTT P42858 1/20 0.36
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23976280 0.81 ADRB2 (0.53) ADRB1ADRB2MEN1KMT2ACYP2D6
SCHEMBL1242805 0.80 KDM4E (0.37)
SCHEMBL12621160 0.80 USP2 (0.40) HTTCYP1A2
SCHEMBL27965038 0.79 HSD17B10 (0.45) HTT
SCHEMBL1245261 0.78 HTT (0.53) MEN1KMT2AHTTCYP1A2
SCHEMBL1244423 0.77 KDM4E (0.34)
SCHEMBL1245435 0.77 KDM4E (0.32) MEN1KMT2A
SCHEMBL1245440 0.77 KDM4E (0.32)
SCHEMBL1244254 0.77 USP2 (0.35) HTT
SCHEMBL1245437 0.76 KDM4E (0.33) ADRB2MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2124545-B1 HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS MOMENTIVE PERFORMANCE MAT INC (US) 2015-12-02 EP disclosed
EP-2124545-B1 HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS MOMENTIVE PERFORMANCE MAT INC (US) 2015-12-02 EP disclosed
US-8569385-B2 Hydrolysis resistant organomodified silylated ionic surfactants MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-10-29 US disclosed
US-8569385-B2 Hydrolysis resistant organomodified silylated ionic surfactants MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-10-29 US disclosed
US-20110105428-A1 HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-05-05 US disclosed
US-7879916-B2 Anionic, cationic or zwitterionic disilane surfactants; stable over a wide pH range; for controlling wetting, spreading, foaming, and detergency on applied surfaces; aqueous solutions improve delivery of active ingredients MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-02-01 US disclosed
US-7879916-B2 Anionic, cationic or zwitterionic disilane surfactants; stable over a wide pH range; for controlling wetting, spreading, foaming, and detergency on applied surfaces; aqueous solutions improve delivery of active ingredients MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-02-01 US disclosed
EP-2124544-A1 HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS Momentive Performance Materials Inc. (US) 2009-12-02 EP disclosed
EP-2124545-A1 HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS Momentive Performance Materials Inc. (US) 2009-12-02 EP disclosed
US-20080167389-A1 Hydrolysis resistant organomodified silylated ionic surfactants MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-07-10 US disclosed
US-20080167269-A1 HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-07-10 US disclosed
US-20080167269-A1 HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-07-10 US disclosed
US-20080167389-A1 Hydrolysis resistant organomodified silylated ionic surfactants MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-07-10 US disclosed
WO-2008073397-A1 HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-06-19 WO disclosed
WO-2008073396-A1 HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-06-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110105428-A1 HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS MLNR, SSTR3, FOXM1 ADRB1 353/4885ADRB2 608/4885MEN1 1587/4885
US-20080167389-A1 Hydrolysis resistant organomodified silylated ionic surfactants MLNR, SSTR3, FOXM1 ADRB1 353/4885ADRB2 608/4885MEN1 1587/4885
US-20080167269-A1 HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS MLNR, SSTR3, FOXM1 ADRB1 353/4885ADRB2 608/4885MEN1 1587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.