Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | RAB9A | P51151 | 5/20 | 0.68 |
| ▸ | HPGD | P15428 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29535799 | 1.00 | NPC1 (0.68) | NPC1SMN1; SMN2RAB9AHPGDALDH1A1 | |
| SCHEMBL1245832 | 0.90 | MEN1 (0.70) | NPC1SMN1; SMN2RAB9AHPGDALDH1A1 | |
| SCHEMBL29535974 | 0.90 | MEN1 (0.70) | NPC1SMN1; SMN2RAB9AHPGDALDH1A1 | |
| SCHEMBL224762 | 0.87 | NPC1 (0.88) | NPC1SMN1; SMN2RAB9AHPGDALDH1A1 | |
| SCHEMBL4731182 | 0.85 | NPC1 (0.86) | NPC1SMN1; SMN2RAB9AHPGDALDH1A1 | |
| SCHEMBL38652442 | 0.83 | NPC1 (0.76) | NPC1SMN1; SMN2RAB9AHPGDALDH1A1 | |
| SCHEMBL3817844 | 0.83 | NPC1 (0.76) | NPC1SMN1; SMN2RAB9AHPGDALDH1A1 | |
| SCHEMBL1039742 | 0.82 | SMN1; SMN2 (0.70) | NPC1SMN1; SMN2RAB9AHPGDALDH1A1 | |
| Ononetin SCHEMBL2948430 | 0.81 | NPC1 (1.00) | NPC1SMN1; SMN2RAB9AHPGDALDH1A1 | |
| SCHEMBL3811897 | 0.81 | NPC1 (0.74) | NPC1SMN1; SMN2RAB9AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383200-B1 | COMPOSITIONS | SYMRISE AG (DE) | 2019-11-06 | — | — | EP | claimed |
| US-20190289886-A1 | SUBSTANCE MIXTURES | SYMRISE AG (DE) | 2019-09-26 | — | — | US | claimed |
| WO-2011024197-A1 | PROCESS FOR PRODUCING A REDUCED BULK DENSITY SUCRALOSE CONTAINING SWEETENER SYSTEM AND PRODUCTS THEREOF | V.B. MEDICARE PVT. LTD. (IN) | 2011-03-03 | — | — | WO | claimed |
| EP-1868452-B1 | HYDROXYDEOXYBENZOINS AND THE USE THEREOF TO MASK A BITTER TASTE | SYMRISE GMBH & CO KG (DE) | 2009-07-22 | — | — | EP | claimed |
| EP-2008530-A1 | Aroma composition for reducing or suppressing unwanted bitter and astringent impressions | Symrise GmbH & Co. KG (DE) | 2008-12-31 | — | — | EP | claimed |
| US-20080317923-A1 | AROMA COMPOSITION FOR REDUCING OR SUPPRESSING AN UNDESIRED BITTER, ASTRINGENT IMPRESSION | SYMRISE GMBH & CO. KG (DE) | 2008-12-25 | — | — | US | claimed |
| EP-2001448-A2 | FLAVOR-ENHANCING COMPOSITIONS, METHODS OF MANUFACTURE, AND METHODS OF USE | Cadbury Adams USA LLC (US) | 2008-12-17 | — | — | EP | claimed |
| US-20080113073-A1 | Hydroxydeoxybenzoins And The Use Thereof to Mask A Bitter Taste | SYMRISE GMBH & CO. KG (DE) | 2008-05-15 | — | — | US | claimed |
| EP-1868452-A1 | HYDROXYDEOXYBENZOINS AND THE USE THEREOF TO MASK A BITTER TASTE | Symrise GmbH & Co. KG (DE) | 2007-12-26 | — | — | EP | claimed |
| WO-2007089652-A2 | FLAVOR-ENHANCING COMPOSITIONS, METHODS OF MANUFACTURE, AND METHODS OF USE | CADBURY ADAMS USA LLC (US) | 2007-08-09 | — | — | WO | claimed |
| US-20070178123-A1 | FLAVOR-ENHANCING COMPOSITIONS, METHOD OF MANUFACTURE, AND METHODS OF USE | KRAFT FOODS GLOBAL BRANDS LLC | 2007-08-02 | — | — | US | claimed |
| WO-2006106023-A1 | HYDROXYDEOXYBENZOINS AND THE USE THEREOF TO MASK A BITTER TASTE | SYMRISE GMBH & CO. KG (DE) | 2006-10-12 | — | — | WO | claimed |
| EP-3454825-B1 | AROMA PREPARATIONS CONTAINING MENTHOL | SYMRISE AG (DE) | 2026-05-06 | — | — | EP | disclosed |
| EP-3911172-B1 | COMBINATION OF SATIETY COMPONENTS WITH ARGININE | SYMRISE AG (DE) | 2026-04-15 | — | — | EP | disclosed |
| US-20260014103-A1 | COMBINATION REMEDY | SYMRISE AG (DE) | 2026-01-15 | — | — | US | disclosed |
| EP-3823455-B1 | COMPOSITION FOR SUBSTITUTING SUGAR IN BAKED GOODS | SYMRISE AG (DE) | 2025-10-01 | — | — | EP | disclosed |
| US-20070178123-A1 | FLAVOR-ENHANCING COMPOSITIONS, METHOD OF MANUFACTURE, AND METHODS OF USE | KRAFT FOODS GLOBAL BRANDS LLC | 2007-08-02 | — | — | US | disclosed |
| WO-2007014879-A1 | USE OF HESPERETIN FOR ENHANCING THE SWEET TASTE | SYMRISE GMBH & CO. KG (DE) | 2007-02-08 | — | — | WO | disclosed |
| WO-2007003527-A1 | HYDROXYPHENYLALKADIONES AND THEIR USE FOR MASKING BITTER TASTE AND/OR FOR INTENSIFYING SWEET TASTE | SYMRISE GMBH & CO. KG (DE) | 2007-01-11 | — | — | WO | disclosed |
| WO-2006106023-A1 | HYDROXYDEOXYBENZOINS AND THE USE THEREOF TO MASK A BITTER TASTE | SYMRISE GMBH & CO. KG (DE) | 2006-10-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260014103-A1 | COMBINATION REMEDY | TAS2R43, TAS2R41, TAS2R60 | NPC1 2419/4885SMN1; SMN2 290/4885RAB9A 3431/4885 |
| US-20190289886-A1 | SUBSTANCE MIXTURES | PNN, NISCH, HES1 | NPC1 1331/4885SMN1; SMN2 2785/4885RAB9A 3442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.