SCHEMBL29535974

SCHEMBL29535974

COc1cc(CC(=O)c2ccc(O)cc2O)ccc1O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.70
KMT2A Q03164 5/20 0.70
SMN1; SMN2 Q16637 5/20 0.70
HPGD P15428 4/20 0.70
ALDH1A1 P00352 3/20 0.70
NPC1 O15118 3/20 0.70
RAB9A P51151 3/20 0.70
CYP3A4 P08684 1/20 0.70
ATM Q13315 1/20 0.70
ESR1 P03372 1/20 0.65
SHBG P04278 1/20 0.65
ESR2 Q92731 1/20 0.65
TTR P02766 1/20 0.63
GAA P10253 3/20 0.61
NFKB1 P19838 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
TSHR P16473 1/20 0.61
LMNA P02545 5/20 0.58
MAPT P10636 3/20 0.58
HTT P42858 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1245832 1.00 MEN1 (0.70) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL1039742 0.91 SMN1; SMN2 (0.70) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL29535799 0.90 NPC1 (0.68) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL1245285 0.90 NPC1 (0.68) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL31511913 0.89 SMN1; SMN2 (0.70) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL8168221 0.89 SMN1; SMN2 (0.70) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL1840837 0.86 MEN1 (0.67) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL14156958 0.86 ESR1 (0.61) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
SCHEMBL31511909 0.86 MEN1 (0.67) MEN1KMT2ASMN1; SMN2HPGDALDH1A1
Ononetin SCHEMBL2948430 0.82 NPC1 (1.00) MEN1KMT2ASMN1; SMN2HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108366597-B Substance mixture 西姆莱斯有限公司 2022-09-02 CN claimed
US-12557831-B2 Mogrosides and uses of the same THE COCA-COLA COMPANY (US) 2026-02-24 US disclosed
EP-3522737-B1 DITERPENE GLYCOSIDES CONTAINING AN ENT-ATISENE CORE, COMPOSITIONS AND METHODS COCA COLA CO (US) 2025-12-03 EP disclosed
US-20250084049-A1 POLYCATIONIC SALTS OF PHENOLIC COMPOUNDS AND USES THEREOF FIRMENICH INCORPORATED (US) 2025-03-13 US disclosed
EP-3528640-B1 DITERPENE GLYCOSIDES ISOLATED FROM STEVIA, COMPOSITIONS AND METHODS COCA COLA CO (US) 2025-01-15 EP disclosed
EP-4469439-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2024-12-04 EP disclosed
CN-118984825-A Novel cooling agent and preparation containing same 西姆莱斯股份公司 2024-11-19 CN disclosed
EP-4452941-A1 ACTIVE INGREDIENTS WITH SIALAGOGUE AND TINGLING/FIZZY EFFECT, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2024-10-30 EP disclosed
EP-4247791-A2 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2023-09-27 EP disclosed
CN-116685575-A Novel cooling substances and formulations containing these cooling substances 西姆莱斯股份公司 2023-09-01 CN disclosed
WO-2023144326-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2023-08-03 WO disclosed
WO-2023143741-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2023-08-03 WO disclosed
CN-109890221-B Diterpene glycosides containing an ent-acteosene core, compositions, and methods 可口可乐公司 2023-04-14 CN disclosed
US-20230115269-A1 Diterpene Glycosides Isolated from Stevia, Compositions and Methods THE COCA-COLA COMPANY 2023-04-13 US disclosed
EP-4103575-A1 ALLULOSE IN CRYSTALLINE FORM Savanna Ingredients GmbH (DE) 2022-12-21 EP disclosed
CN-108366597-B Substance mixture 西姆莱斯有限公司 2022-09-02 CN disclosed
WO-2022106452-A2 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2022-05-27 WO disclosed
WO-2022105986-A1 NOVEL COOLING AGENTS AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2022-05-27 WO disclosed
CN-109310130-B Cooling substance mixture 西姆莱斯股份公司 2022-05-17 CN disclosed
US-20220142216-A1 Novel Mogrosides and Uses of the Same THE COCA-COLA COMPANY 2022-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250084049-A1 POLYCATIONIC SALTS OF PHENOLIC COMPOUNDS AND USES THEREOF PGC, SLC5A6, PUF60 MEN1 2672/4885KMT2A 741/4885SMN1; SMN2 2952/4885
US-12557831-B2 Mogrosides and uses of the same TAS2R40, TAS2R20, TAS2R10 MEN1 2170/4885KMT2A 1530/4885SMN1; SMN2 1588/4885
US-20230115269-A1 Diterpene Glycosides Isolated from Stevia, Compositions and Methods GYPA, DDOST, TAS2R7 MEN1 1532/4885KMT2A 2952/4885SMN1; SMN2 3193/4885
US-20220142216-A1 Novel Mogrosides and Uses of the Same MAG, UGGT1, OGT MEN1 1686/4885KMT2A 3389/4885SMN1; SMN2 983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.