SCHEMBL1245327

SCHEMBL1245327

O=P1(O)OCC(c2ccccc2)O1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.47
TSHR P16473 2/20 0.47
CYP19A1 P11511 3/20 0.35
AR P10275 2/20 0.35
MAOB P27338 2/20 0.35
HSD17B10 Q99714 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
EPHX1 P07099 1/20 0.34
MAOA P21397 1/20 0.33
PSMB5 P28074 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
CYP1A1 P04798 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP1B1 Q16678 1/20 0.32
PLK1 P53350 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28795330 0.82 DGAT1 (0.39) DGAT1TSHRCYP19A1ALDH1A1KMT2A
SCHEMBL22785961 0.78 TSHR (0.47) DGAT1TSHRCYP19A1ARMAOB
SCHEMBL24015447 0.78 TSHR (0.47) DGAT1TSHRCYP19A1ARMAOB
SCHEMBL10713916 0.77 DGAT1 (0.36) DGAT1TSHREPHX1CYP2C9CYP2C19
SCHEMBL22785822 0.74 TSHR (0.42) TSHRCYP19A1ARMAOBHSD17B10
SCHEMBL24014985 0.74 TSHR (0.42) TSHRCYP19A1ARMAOBHSD17B10
SCHEMBL887374 0.71 MAPK1 (0.42) DGAT1TSHREPHX1CYP2C19
SCHEMBL887405 0.71 MAPK1 (0.42) DGAT1TSHREPHX1CYP2C19
SCHEMBL887275 0.71 MAPK1 (0.42) DGAT1TSHREPHX1CYP2C19
SCHEMBL31574623 0.70 MAPK1 (0.41) DGAT1TSHRKDM4EEPHX1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010049025-A1 Multilayer films having flame retardant layers 3M INNOVATIVE PROPERTIES COMPANY 2001-12-06 US claimed
EP-3562979-B1 DIMENSIONALLY-STABLE, FIRE-RESISTANT MELT-BLOWN FIBERS AND NONWOVEN STRUCTURES INCLUDING A FLAME RETARDING POLYMER 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-01-24 EP disclosed
CN-112074565-B Moisture curable polyolefin formulations 联合碳化公司 2023-01-31 CN disclosed
US-20210095405-A1 CERAMIC-COATED FIBERS INCLUDING A FLAME-RETARDING POLYMER, AND METHODS OF MAKING NONWOVEN STRUCTURES 3M INNOVATIVE PROPERTIES COMPANY 2021-04-01 US disclosed
EP-3732251-A2 CERAMIC-COATED FIBERS INCLUDING A FLAME-RETARDING POLYMER, AND METHODS OF MAKING NONWOVEN STRUCTURES 3M Innovative Properties Company (US) 2020-11-04 EP disclosed
US-20200071865-A1 DIMENSIONALLY-STABLE, FIRE-RESISTANT MELT-BLOWN FIBERS AND NONWOVEN STRUCTURES INCLUDING A FLAME RETARDING POLYMER 3M INNOVATIVE PROPERTIES COMPANY 2020-03-05 US disclosed
EP-3562979-A1 DIMENSIONALLY-STABLE, FIRE-RESISTANT MELT-BLOWN FIBERS AND NONWOVEN STRUCTURES INCLUDING A FLAME RETARDING POLYMER 3M Innovative Properties Company (US) 2019-11-06 EP disclosed
WO-2018126085-A1 DIMENSIONALLY-STABLE, FIRE-RESISTANT MELT-BLOWN FIBERS AND NONWOVEN STRUCTURES INCLUDING A FLAME RETARDING POLYMER 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-07-05 WO disclosed
CN-102762653-B For the halogen-free flame retardant thermoplastic compositions of electric wire and cable application DOW GLOBAL TECHNOLOGIES LLC (US) 2015-11-25 CN disclosed
CN-103370368-B Halogen-free flame retardant compositions for wire and cable applications DOW GLOBAL TECHNOLOGIES LLC (US) 2015-11-25 CN disclosed
US-4097446-A Reinforced intercrystalline thermoplastic polyester compositions GENERAL ELECTRIC COMPANY (US) 1978-06-27 US disclosed
US-4020124-A Blends of a polyphenylene ether resin, alkenyl aromatic resins modified with EPDM rubber and graft polymerized high rubber content polymers GENERAL ELECTRIC COMPANY (US) 1977-04-26 US disclosed
US-4013613-A INCLUDING ADDITION POLYMER GENERAL ELECTRIC COMPANY (US) 1977-03-22 US disclosed
US-4002581-A MOLDINGS GENERAL ELECTRIC COMPANY (US) 1977-01-11 US disclosed
US-3981841-A MOLDING MATERIALS, IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1976-09-21 US disclosed
US-3974235-A Blends of a polyphenylene ether resin, alkenyl aromatic resins modified with EPDM rubber and flame retardant GENERAL ELECTRIC COMPANY (US) 1976-08-10 US disclosed
US-3959211-A ETHYLENE-ALPHA-OLEFIN-DIENE GENERAL ELECTRIC COMPANY (US) 1976-05-25 US disclosed
US-3953394-A POLYETHYLENE TEREPHTHALATE-POLYBUTYLENE TEREPHTHALATE BLENDS GENERAL ELECTRIC COMPANY (US) 1976-04-27 US disclosed
US-3950301-A HYDROXYBENZOTRIAZOLES, FIREPROOFING GENERAL ELECTRIC COMPANY (US) 1976-04-13 US disclosed
US-3943191-A MOLDING GENERAL ELECTRIC COMPANY (US) 1976-03-09 US disclosed