Sugi Predict

Sugi Predict / Targets / CLTC

CLTC

Clathrin heavy chain 1 · Q00610 · CLTC on Sugi Atlas →

979 patent compounds predicted against CLTC, 695 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL14636024 SCHEMBL14636024 0.79 14/20
SCHEMBL14652610 SCHEMBL14652610 0.64 14/20
SCHEMBL14636004 SCHEMBL14636004 0.79 13/20
SCHEMBL14636558 SCHEMBL14636558 0.79 13/20
SCHEMBL14635627 SCHEMBL14635627 0.78 13/20
SCHEMBL14636234 SCHEMBL14636234 0.78 13/20
SCHEMBL14636718 SCHEMBL14636718 0.78 13/20
SCHEMBL14636868 SCHEMBL14636868 0.78 13/20
SCHEMBL14636859 SCHEMBL14636859 0.77 13/20
SCHEMBL14636506 SCHEMBL14636506 0.67 13/20
SCHEMBL14635611 SCHEMBL14635611 0.62 13/20
SCHEMBL7848586 SCHEMBL7848586 0.48 13/20
SCHEMBL6346852 SCHEMBL6346852 0.54 12/20
SCHEMBL14557200 SCHEMBL14557200 0.64 11/20
SCHEMBL20506114 SCHEMBL20506114 0.38 11/20
SCHEMBL14636204 SCHEMBL14636204 0.72 10/20
SCHEMBL14635858 SCHEMBL14635858 0.64 10/20
SCHEMBL2365089 SCHEMBL2365089 0.58 10/20
SCHEMBL2365090 SCHEMBL2365090 0.58 10/20
SCHEMBL11745447 SCHEMBL11745447 0.44 10/20

Clinical trials — most relevant to CLTC by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Treatment of Ectopic Calcification in Fahr's Disease or Syndrome PHASE2RECRUITING
Erlotinib and Surgery in Treating Patients With Head and Neck Cancer That Can Be Removed by Surgery EARLY_PHASE1COMPLETED
Prevalence and Risk Factors of Nephrocalcinosis in Children at Sohag University Hospital nanUNKNOWN
Signs and Symptoms of Genetic Abnormalities Linked to Inherited Heart Disease nanCOMPLETED
Natural History of Neuronal Ceroid Lipofuscinosis, Batten's CLN6 Diseae nanACTIVE_NOT_RECRUITING
Defining the Genetic Etiology of Alzheimer's Disease in the Faroe Islands nanUNKNOWN
Immune Cell Response to Stimuli nanRECRUITING
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
A Natural History Study of Neuronal Ceroid Lipofuscinosis Type 5 (CLN5) nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Markers and Mechanisms of Macrovascular Disease in IDDM nanCOMPLETED
Insulin Detemir in Obesity Management nanACTIVE_NOT_RECRUITING
Comparison of Two Methods to Diagnose Coronary Artery Disease nanCOMPLETED
Corpus Callosum Agenesis and Intellectual Disability nanCOMPLETED
Clinical and Genetic Analysis in Congenital Hypothyroidism Due to Thyroid Dysgenesis. nanCOMPLETED
Epidemiology of Atherosclerosis nanCOMPLETED
Signs and Symptoms Associated With Molecular Defects in Genetically Inherited Heart Disease nanCOMPLETED
Endothelial Colony-Forming Cells in Patients With VWD, AVWS and Healthy Subjects nanRECRUITING
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
5-Aminolevulinic Acid (5-ALA) to Enhance Visualization of Malignant Tumor nanCOMPLETED
Study of Chediak-Higashi Syndrome nanRECRUITING
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Nuclear Myosin VI - a Therapeutic Target in Breast Cancer nanUNKNOWN
Defining an Obesity QTL on Chromosome 3q nanCOMPLETED
Family Blood Pressure Program - GENOA nanCOMPLETED
Gene Expression, Metabolomic, Microbiome, and Calcium Metabolism in Response to Varied Vitamin D Dosages nanCOMPLETED
Assessment Of Long Noncoding RNA CCAT1 In Colorectal Cancer Patients nanUNKNOWN
Gene Expression in Inflammatory Bowel Disease nanENROLLING_BY_INVITATION
Chromosome 5Q Gene Variants and Asthma-Related Traits nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a CLTC binder may also engage these)

ProteinNameSimilarity
P49951 — 1.000 P49951 →
Q68FD5 — 1.000 Q68FD5 →
P11442 — 1.000 P11442 →
P29742 — 1.000 P29742 →
P53675 — 1.000 P53675 →
P34574 — 0.998 P34574 →
Q2RBN7 — 0.997 Q2RBN7 →
P22137 — 0.996 P22137 →
P25870 — 0.996 P25870 →
Q0WNJ6 — 0.996 Q0WNJ6 →
Q0WLB5 — 0.996 Q0WLB5 →
Q2QYW2 — 0.995 Q2QYW2 →
Q10161 — 0.993 Q10161 →
Q22830 — 0.990 Q22830 →
O74925 — 0.989 O74925 →
Q24314 — 0.989 Q24314 →
Q5U2N8 — 0.988 Q5U2N8 →
Q03308 — 0.987 Q03308 →
Q8C3Y4 — 0.987 Q8C3Y4 →
Q95QT8 — 0.987 Q95QT8 →
Q8WUM0 — 0.987 Q8WUM0 →
Q19954 — 0.987 Q19954 →
Q9STV0 — 0.986 Q9STV0 →
Q9W040 — 0.985 Q9W040 →
Q9VT41 — 0.985 Q9VT41 →
Q09600 — 0.985 Q09600 →
ELP1 Elongator complex protein 1 0.985 landscape →
Q61LA1 — 0.985 Q61LA1 →
Q9VRX1 — 0.985 Q9VRX1 →
A8JA42 — 0.985 A8JA42 →