Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 2/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12457045 | 0.87 | DHFR (0.36) | CDK1CCNB1CCNE1CDK2MAPKAPK2 | |
| SCHEMBL12393901 | 0.84 | MAPKAPK2 (0.41) | MAPKAPK2 | |
| SCHEMBL10268684 | 0.78 | CDK1 (0.38) | CDK1CCNB1CCNE1CDK2MAPKAPK2 | |
| SCHEMBL12457199 | 0.73 | CDK1 (0.35) | CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL27112701 | 0.70 | SRC (0.35) | — | |
| SCHEMBL10212549 | 0.66 | MAPKAPK2 (0.44) | MAPKAPK2 | |
| SCHEMBL12393894 | 0.63 | HRH4 (0.33) | — | |
| SCHEMBL20324023 | 0.62 | CLK1 (0.45) | CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL24340238 | 0.62 | DHFR (0.35) | CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL12473793 | 0.62 | ADORA1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008481-B2 | Indazole compounds | ABBVIE INC. | 2011-08-30 | — | — | US | disclosed |