Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.49 |
| ▸ | FAAH | O00519 | 4/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.44 |
| ▸ | TERT | O14746 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909090 | 0.98 | KCNH2 (0.50) | KCNH2FAAHTRPV1EPHX2TERT | |
| SCHEMBL10065914 | 0.89 | FAAH (0.54) | KCNH2FAAHTRPV1EPHX2TERT | |
| SCHEMBL15534858 | 0.89 | FAAH (0.54) | KCNH2FAAHTRPV1EPHX2TERT | |
| SCHEMBL12458477 | 0.89 | FAAH (0.54) | KCNH2FAAHTRPV1EPHX2TERT | |
| SCHEMBL18525113 | 0.89 | FAAH (0.54) | KCNH2FAAHTRPV1EPHX2TERT | |
| SCHEMBL25382057 | 0.89 | FAAH (0.54) | KCNH2FAAHTRPV1EPHX2TERT | |
| SCHEMBL4950503 | 0.89 | FAAH (0.54) | KCNH2FAAHTRPV1EPHX2TERT | |
| SCHEMBL11686302 | 0.89 | KCNH2 (0.53) | KCNH2 | |
| SCHEMBL11683035 | 0.89 | KCNH2 (0.53) | KCNH2 | |
| SCHEMBL9016980 | 0.89 | KCNH2 (0.53) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120238747-A1 | TRANSFECTION REAGENTS | Life Technologies Corporation (US) | 2012-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238747-A1 | TRANSFECTION REAGENTS | CPS1, PHAX, HNRNPH3 | KCNH2 400/4885FAAH 4748/4885TRPV1 3137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.