SCHEMBL1245876

SCHEMBL1245876

O=C(COc1ccc2sc3ccccc3c(=O)c2c1)OCCO

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.53
MAPT P10636 3/20 0.53
ALDH1A1 P00352 3/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
MAOA P21397 3/20 0.41
MAOB P27338 3/20 0.41
PTPN7 P35236 1/20 0.40
DUSP3 P51452 1/20 0.40
PTPN12 Q05209 1/20 0.40
PTPN22 Q9Y2R2 1/20 0.40
GAA P10253 1/20 0.40
HPGD P15428 2/20 0.39
KMT2A Q03164 2/20 0.39
ACSL1 P33121 2/20 0.39
ACSL6 Q9UKU0 2/20 0.39
MEN1 O00255 1/20 0.39
HCRTR1 O43613 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14209211 0.94 KDM4E (0.57) KDM4EMAPTALDH1A1NPC1RAB9A
SCHEMBL13260786 0.92 KDM4E (0.54) KDM4EMAPTALDH1A1NPC1RAB9A
SCHEMBL14209284 0.91 KDM4E (0.53) KDM4EMAPTALDH1A1NPC1RAB9A
SCHEMBL278707 0.91 KDM4E (0.53) KDM4EMAPTALDH1A1NPC1RAB9A
SCHEMBL18400539 0.90 KDM4E (0.56) KDM4EMAPTALDH1A1NPC1RAB9A
SCHEMBL14845442 0.90 KDM4E (0.58) KDM4EMAPTALDH1A1NPC1RAB9A
SCHEMBL7933557 0.89 KDM4E (0.62) KDM4EMAPTALDH1A1NPC1RAB9A
Hydrochloric Acid SCHEMBL15392382 0.88 KDM4E (0.51) KDM4EMAPTALDH1A1NPC1RAB9A
SCHEMBL16785826 0.88 KDM4E (0.51) KDM4EMAPTALDH1A1NPC1RAB9A
SCHEMBL278860 0.88 KDM4E (0.57) KDM4EMAPTALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2394676-B1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITIATOR-CONTAINING SCAFFOLDS COLOPLAST AS (DK) 2018-03-28 EP disclosed
CN-103468108-B Coating composition COLOPLAST A/S (DK) 2016-03-02 CN disclosed
EP-2459242-B1 A MEDICAL DEVICE OF POLYOLEFIN COLOPLAST AS (DK) 2015-10-21 EP disclosed
EP-2104523-B1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST AS (DK) 2015-08-26 EP disclosed
US-8932662-B2 Coatings prepared from poly(ethylene oxide) and photo-initator-containing scaffolds COLOPLAST A/S (DK) 2015-01-13 US disclosed
CN-103468108-A Coating composition COLOPLAST AS 2013-12-25 CN disclosed
EP-2459242-A2 A MEDICAL DEVICE OF POLYOLEFIN Coloplast A/S (DK) 2012-06-06 EP disclosed
US-20120121919-A1 MEDICAL DEVICE OF POLYOLEFIN COLOPLAST A/S (DK) 2012-05-17 US disclosed
WO-2011012137-A2 A MEDICAL DEVICE OF POLYOLEFIN COLOPLAST A/S (DK) 2011-02-03 WO disclosed
US-20100049146-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST A/S (DK) 2010-02-25 US disclosed
EP-2104523-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS Coloplast A/S (DK) 2009-09-30 EP disclosed
WO-2008071796-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST A/S (DK) 2008-06-19 WO disclosed