SCHEMBL7933557

SCHEMBL7933557

O=c1c2ccccc2sc2ccc(OCCO)cc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.62
ALDH1A1 P00352 3/20 0.62
NPC1 O15118 2/20 0.62
MAPT P10636 2/20 0.62
RAB9A P51151 2/20 0.62
TDP1 Q9NUW8 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
MAOA P21397 6/20 0.48
MAOB P27338 6/20 0.48
PTPN7 P35236 1/20 0.43
DUSP3 P51452 1/20 0.43
PTPN12 Q05209 1/20 0.43
PTPN22 Q9Y2R2 1/20 0.43
RECQL P46063 1/20 0.42
ACSL1 P33121 2/20 0.41
ACSL6 Q9UKU0 2/20 0.41
MEN1 O00255 1/20 0.41
HCRTR1 O43613 1/20 0.41
HPGD P15428 1/20 0.41
NFKB1 P19838 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1245876 0.89 KDM4E (0.53) KDM4EALDH1A1NPC1MAPTRAB9A
SCHEMBL30845908 0.88 PTPN7 (0.50) KDM4EALDH1A1NPC1MAPTRAB9A
SCHEMBL1505814 0.86 MAPT (0.67) KDM4EALDH1A1NPC1MAPTRAB9A
SCHEMBL1469810 0.86 KDM4E (0.62) KDM4EALDH1A1NPC1MAPTRAB9A
SCHEMBL10958084 0.85 KDM4E (0.58) KDM4EALDH1A1NPC1MAPTRAB9A
SCHEMBL2293712 0.85 KDM4E (0.58) KDM4EALDH1A1NPC1MAPTRAB9A
SCHEMBL12795345 0.84 MAOA (0.55) KDM4EALDH1A1NPC1MAPTRAB9A
SCHEMBL24949252 0.84 KDM4E (0.57) KDM4EALDH1A1NPC1MAPTRAB9A
SCHEMBL10932212 0.84 ACSL1 (0.58) KDM4EALDH1A1NPC1MAPTRAB9A
SCHEMBL14209211 0.84 KDM4E (0.57) KDM4EALDH1A1NPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230256753-A1 INK JET PRINTING METHOD, INK JET PRINTING APPARATUS, METHOD OF PRODUCING POROUS BODY, AND APPARATUS FOR PRODUCING POROUS BODY CANON KABUSHIKI KAISHA (JP) 2023-08-17 US disclosed
US-20160195808-A1 REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES TOYO GOSEI CO LTD (JP) 2016-07-07 US disclosed
US-20160147144-A1 REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES TOYO GOSEI CO., LTD (JP) 2016-05-26 US disclosed
WO-2015022779-A1 REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES TOYO GOSEI CO., LTD. (JP) 2015-02-19 WO disclosed
WO-2014208102-A1 Reagent for Enhancing Generation of Chemical Species TOYO GOSEI CO., LTD. (JP) 2014-12-31 WO disclosed
US-8158746-B2 Active energy ray curable liquid composition and liquid cartridge CANON KABUSHIKI KAISHA (JP) 2012-04-17 US disclosed
US-8124791-B2 Active energy ray curable liquid composition and liquid cartridge CANON KABUSHIKI KAISHA (JP) 2012-02-28 US disclosed
US-7976148-B2 Active energy ray curable aqueous ink composition, and inkjet recording method, ink cartridge, recording unit, and inkjet recording apparatus using the same CANON KABUSHIKI KAISHA (JP) 2011-07-12 US disclosed
US-20100324163-A1 ACTIVE ENERGY RAY CURABLE LIQUID COMPOSITION AND LIQUID CARTRIDGE CANON KABUSHIKI KAISHA (JP) 2010-12-23 US disclosed
EP-2246330-A1 New photoinitiators Siegwerk Benelux SA (BE) 2010-11-03 EP disclosed
US-20100094024-A1 ACTIVE ENERGY RAY CURABLE LIQUID COMPOSITION AND LIQUID CARTRIDGE CANON KABUSHIKI KAISHA (JP) 2010-04-15 US disclosed
US-20090286001-A1 ACTIVE-ENERGY RADIATION-POLYMERIZABLE SUBSTANCE, ACTIVE-ENERGY RADIATION-CURABLE LIQUID COMPOSITION, ACTIVE-ENERGY RADIATION-CURABLE INK, INK JET RECORDING METHOD, INK CARTRIDGE, RECORDING UNIT, AND INK JET RECORDING APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-11-19 US disclosed
US-6245922-B1 PREPARED BY REACTING AN ELECTROPHILIC 2-ALKENYL AZALACTONE WITH A NUCLEOPHILIC AROMATIC KETONE; CAN BE COPOLYMERIZED WITH ACRYLIC MONOMERS AND PHOTOACTIVATED BY ACTINIC RADIATION TO CROSSLINK THE POLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2001-06-12 US disclosed
EP-0837844-B1 ACRYLAMIDE DERIVATIVES AS CHROMOPHORIC PHOTOCROSSLINKING COMPOUND MINNESOTA MINING & MFG (US) 2000-04-05 EP disclosed
EP-0837844-A1 ACRYLAMIDE DERIVATIVES AS CHROMOPHORIC PHOTOCROSSLINKING COMPOUND MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-04-29 EP disclosed
WO-1997005101-A1 ACRYLAMIDE DERIVATIVES AS CHROMOPHORIC PHOTOCROSSLINKING COMPOUND MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-02-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090286001-A1 ACTIVE-ENERGY RADIATION-POLYMERIZABLE SUBSTANCE, ACTIVE-ENERGY RADIATION-CURABLE LIQUID COMPOSITION, ACTIVE-ENERGY RADIATION-CURABLE INK, INK JET RECORDING METHOD, INK CARTRIDGE, RECORDING UNIT, AND INK JET RECORDING APPARATUS DACH1, MMP1, IDUA KDM4E 2356/4885ALDH1A1 591/4885NPC1 4711/4885
US-20100094024-A1 ACTIVE ENERGY RAY CURABLE LIQUID COMPOSITION AND LIQUID CARTRIDGE C9, MLX, CHRM1 KDM4E 2960/4885ALDH1A1 3555/4885NPC1 3731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.