Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.52 |
| ▸ | CDC42 | P60953 | 1/20 | 0.52 |
| ▸ | RAC1 | P63000 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5604761 | 1.00 | PTGS2 (0.56) | PTGS2TDP1L3MBTL1TSHRLMNA | |
| SCHEMBL13730950 | 1.00 | PTGS2 (0.56) | PTGS2TDP1L3MBTL1TSHRLMNA | |
| Naproxcinod SCHEMBL1448284 | 0.99 | PTGS2 (0.57) | PTGS2TDP1L3MBTL1TSHRLMNA | |
| Naproxcinod SCHEMBL29663794 | 0.99 | PTGS2 (0.57) | PTGS2TDP1L3MBTL1TSHRLMNA | |
| Naproxcinod SCHEMBL1170879 | 0.99 | PTGS2 (0.57) | PTGS2TDP1L3MBTL1TSHRLMNA | |
| SCHEMBL13730523 | 0.97 | PTGS2 (0.57) | PTGS2TDP1L3MBTL1TSHRLMNA | |
| SCHEMBL19719469 | 0.97 | PTGS2 (0.57) | PTGS2TDP1L3MBTL1TSHRLMNA | |
| SCHEMBL218779 | 0.92 | PTGS2 (0.53) | PTGS2TDP1L3MBTL1TSHRLMNA | |
| SCHEMBL19719468 | 0.92 | PTGS2 (0.60) | PTGS2TDP1L3MBTL1TSHRLMNA | |
| SCHEMBL12135362 | 0.91 | TDP1 (0.51) | PTGS2TDP1L3MBTL1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1526839-B1 | ORAL PHARMACEUTICAL FORMS OF LIQUID DRUGS HAVING IMPROVED BIOAVAILABILITY | NICOX SA (FR) | 2007-03-14 | — | — | EP | claimed |
| US-20060171969-A1 | Oral pharmaceutical forms of liquid drugs having improved bioavailability | NICOX S.A. (FR) | 2006-08-03 | — | — | US | claimed |
| WO-2011012400-A2 | NITRIC OXIDE RELEASING NAPROXEN | NICOX S.A. (FR) | 2011-02-03 | — | — | WO | disclosed |
| EP-1526839-B1 | ORAL PHARMACEUTICAL FORMS OF LIQUID DRUGS HAVING IMPROVED BIOAVAILABILITY | NICOX SA (FR) | 2007-03-14 | — | — | EP | disclosed |
| US-20060171969-A1 | Oral pharmaceutical forms of liquid drugs having improved bioavailability | NICOX S.A. (FR) | 2006-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060171969-A1 | Oral pharmaceutical forms of liquid drugs having improved bioavailability | ABCG2, SLCO1B1, SLCO4C1 | PTGS2 653/4885TDP1 3083/4885L3MBTL1 4851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.