Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.69 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.69 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1246020 | 1.00 | ADRB2 (0.69) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL1246010 | 1.00 | ADRB2 (0.69) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| Formic Acid SCHEMBL28823054 | 0.94 | ADRB2 (0.63) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL1244738 | 0.85 | KMT2A (0.57) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL1244737 | 0.85 | KMT2A (0.57) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL4983780 | 0.85 | ADRB2 (0.55) | ADRB2ADRB1ADRB3ALDH1A1MAPT | |
| SCHEMBL19206103 | 0.84 | ADRB2 (0.57) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL8405253 | 0.84 | ADRB2 (0.64) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL2336328 | 0.83 | ADRB2 (0.71) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL11774862 | 0.82 | ADRB2 (0.55) | ADRB2ADRB1ADRB3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011012400-A2 | NITRIC OXIDE RELEASING NAPROXEN | NICOX S.A. (FR) | 2011-02-03 | — | — | WO | disclosed |
| CN-1164574-C | Phenoxypropylamine compounds | ������ҩ��ʽ���� | 2004-09-01 | — | — | CN | disclosed |
| CN-1378533-A | Phenoxypropylamine compounds | MITSUBISHI PHARMACEUTICAL CO L (JP) | 2002-11-06 | — | — | CN | disclosed |