SCHEMBL12460366

SCHEMBL12460366

CCCC1=NOC(CC)C1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 1/20 0.30
ITGA2B P08514 1/20 0.30
MIF P14174 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10274203 0.83
SCHEMBL12461551 0.77
SCHEMBL12460457 0.77
SCHEMBL27327753 0.73 ITGB3 (0.36) ITGB3ITGA2BMIF
SCHEMBL12203105 0.72
SCHEMBL680131 0.71
SCHEMBL27885864 0.71 MIF (0.35) MIF
SCHEMBL24497382 0.70
SCHEMBL6124951 0.70
SCHEMBL13293702 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1697312-B1 HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF LEO PHARMA AS (DK) 2011-07-20 EP disclosed