Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.49 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.47 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14844630 | 0.85 | MTOR (0.49) | LRRK2SMARCA2SMARCA4BRD4MTOR | |
| SCHEMBL12459916 | 0.85 | LRRK2 (0.51) | LRRK2SMARCA2SMARCA4BRD4MTOR | |
| SCHEMBL12138433 | 0.81 | SMARCA2 (0.43) | LRRK2SMARCA2SMARCA4BRD4MTOR | |
| SCHEMBL3702318 | 0.81 | LRRK2 (0.45) | LRRK2SMARCA2SMARCA4BRD4ALOX5AP | |
| SCHEMBL3702267 | 0.81 | LRRK2 (0.42) | LRRK2SMARCA2SMARCA4BRD4MTOR | |
| SCHEMBL7891617 | 0.80 | GRM2 (0.42) | LRRK2SMARCA2SMARCA4BRD4MTOR | |
| SCHEMBL38650985 | 0.80 | SMARCA2 (0.45) | LRRK2SMARCA2SMARCA4BRD4MAP4K4 | |
| SCHEMBL12395918 | 0.80 | PIK3CD (0.48) | LRRK2ALOX5APFEN1MAP4K4PIK3CD | |
| SCHEMBL12369677 | 0.79 | LRRK2 (0.52) | LRRK2ALOX5APPIK3CDPIK3CAPIK3CB | |
| SCHEMBL31118837 | 0.76 | LCK (0.50) | LRRK2SMARCA2SMARCA4BRD4MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345328-A1 | COMPOSITION FOR AGRICULTURAL USE | Sumitomo Chemical Company, Limited (JP) | 2011-07-20 | — | — | EP | disclosed |