Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1366652 | 0.92 | CYP2D6 (0.42) | CYP2D6MMP13HSD11B1MCL1CYP1A2 | |
| SCHEMBL8015585 | 0.92 | CYP2D6 (0.42) | CYP2D6MMP13HSD11B1MCL1CYP1A2 | |
| SCHEMBL29105266 | 0.92 | CYP2D6 (0.42) | CYP2D6MMP13HSD11B1MCL1CYP1A2 | |
| SCHEMBL29765023 | 0.92 | CYP2D6 (0.42) | CYP2D6MMP13HSD11B1MCL1CYP1A2 | |
| SCHEMBL1366650 | 0.92 | CYP2D6 (0.42) | CYP2D6MMP13HSD11B1MCL1CYP1A2 | |
| SCHEMBL29669271 | 0.90 | CYP2D6 (0.41) | CYP2D6MMP13HSD11B1MCL1CYP1A2 | |
| SCHEMBL12143097 | 0.90 | CYP2D6 (0.42) | CYP2D6MMP13HSD11B1MCL1CYP1A2 | |
| SCHEMBL12143096 | 0.90 | CYP2D6 (0.42) | CYP2D6MMP13HSD11B1MCL1CYP1A2 | |
| SCHEMBL12143104 | 0.90 | CYP2D6 (0.42) | CYP2D6MMP13HSD11B1MCL1CYP1A2 | |
| SCHEMBL1441007 | 0.89 | CYP2D6 (0.38) | CYP2D6MMP13HSD11B1MCL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343286-A1 | Dibenzo[b,f][1,4]oxazepine derivatives as inhibitors of histone deacetylase | Methylgene, Inc. (CA) | 2011-07-13 | — | — | EP | disclosed |